A 43-year-old male with a history of congenital hepatic fibrosis associated with large liver cell dysplasia developed a sizable lesion in the right lobe of the liver, which was, after a follow-up of 4 years, surgically removed on account of a suspected malignant transformation. Pathological examination showed an unencapsulated nodule with both architectural and cytological dysplastic changes, arising in a background of congenital hepatic fibrosis harbouring extranodularfoci of large liver cell dysplasia. This report concerns the development of a high grade dysplastic nodule, a sizable hepatocellular lesion with suspected preneoplastic significance, in a patient with congenital hepatic fibrosis associated with large liver cell dysplasia. Key words: congenital hepatic fibrosis; dysplastic nodule; liver cell: dysplasia.

DEVELOPMENT OF A HIGH GRADE DYSPLASTIC NODULE IN A CASE OF CONGENITAL HEPATIC FIBROSIS

M. RONCALLI;
1999-01-01

Abstract

A 43-year-old male with a history of congenital hepatic fibrosis associated with large liver cell dysplasia developed a sizable lesion in the right lobe of the liver, which was, after a follow-up of 4 years, surgically removed on account of a suspected malignant transformation. Pathological examination showed an unencapsulated nodule with both architectural and cytological dysplastic changes, arising in a background of congenital hepatic fibrosis harbouring extranodularfoci of large liver cell dysplasia. This report concerns the development of a high grade dysplastic nodule, a sizable hepatocellular lesion with suspected preneoplastic significance, in a patient with congenital hepatic fibrosis associated with large liver cell dysplasia. Key words: congenital hepatic fibrosis; dysplastic nodule; liver cell: dysplasia.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11699/14134
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