Porcine dermal xenograft as augmentation in the treatment of large rotator cuff tears: Clinical and magnetic resonance results at 2-year follow-up

Purpose  The aim of the present retrospective study is to describe the results obtained at 2-year follow-up by using a porcine dermis-derived collagen membrane implanted as augmentation to treat large rotator cuff tears. Methods  Thirty-five patients in total were included according to the following criteria: large or massive rotator cuff tear, confirmed during surgery, measuring between 3 and 5 cm in width and stage 1 to 2 fatty infiltration documented at magnetic resonance imaging (MRI). Patients underwent arthroscopic repair of the cuff augmented by the implantation of a porcine dermal collagen membrane. Patients were evaluated up to 24 months after surgery by the Constant score and MRI imaging to assess functional outcomes and re-tear rate. The results obtained were compared to those of a matched cohort of 35 patients operated by arthroscopic repair alone by the same surgical team. Results  The application of the porcine membrane proved to be safe without scaffold-related adverse events documented. A statistically significant difference in the Constant score in favor of the treatment group was documented at the final evaluation ( p  = 0.036 ). Furthermore, a subgroup analysis revealed that patients treated by augmentation and presenting re-tear at MRI showed a significantly higher functional outcome compared with control patients with MRI evidence of re-tear ( p  = 0.0136). Conclusion  Arthroscopic repair augmented by porcine dermal xenograft for the treatment of chronic and retracted rotator cuff tears with low-grade fatty degeneration proved to be safe and also effective, with higher functional score compared with the arthroscopic repair alone. Level of Evidence  This is a Level III, retrospective cohort study.

Purpose The aim of the present retrospective study is to describe the results obtainedat 2-year follow-up by using a porcine dermis-derived collagenmembrane implanted asaugmentation to treat large rotator cuff tears.Methods Thirty-five patients in total were included according to the followingcriteria: large or massive rotator cuff tear, confirmed during surgery, measuringbetween 3 and 5 cm in width and stage 1 to 2 fatty infiltration documented atmagnetic resonance imaging (MRI). Patients underwent arthroscopic repair of the cuffaugmented by the implantation of a porcine dermal collagenmembrane. Patients wereevaluated up to 24 months after surgery by the Constant score and MRI imaging toassess functional outcomes and re-tear rate. The results obtained were compared tothose of a matched cohort of 35 patients operated by arthroscopic repair alone by thesame surgical team.Results The application of the porcine membrane proved to be safe without scaffoldrelatedadverse events documented. A statistically significant difference in theConstant score in favor of the treatment group was documented at the final evaluation(p ¼ 0.036). Furthermore, a subgroup analysis revealed that patients treated byaugmentation and presenting re-tear at MRI showed a significantly higher functionaloutcome compared with control patients with MRI evidence of re-tear (p ¼ 0.0136).Conclusion Arthroscopic repair augmented by porcine dermal xenograft for thetreatment of chronic and retracted rotator cuff tears with low-grade fatty degenerationproved to be safe and also effective, with higher functional score compared with thearthroscopic repair alone.Level of Evidence This is a Level III, retrospective cohort study.