β-thymosins play roles in cytoskeleton rearrangement, angiogenesis, fibrosis and reparative process, thus suggesting a possible involvement in the pathogenesis of systemic sclerosis. The aim of the study was to investigate the presence of thymosins β4, β4 sulfoxide, and β10 in bronchoalveolar lavage fluid of scleroderma patients with interstitial lung disease and the relation of these factors with pulmonary functional and radiological parameters.

β-Thymosins and interstitial lung disease: study of a scleroderma cohort with a one-year follow-up

De Santis, Maria;
2011

Abstract

β-thymosins play roles in cytoskeleton rearrangement, angiogenesis, fibrosis and reparative process, thus suggesting a possible involvement in the pathogenesis of systemic sclerosis. The aim of the study was to investigate the presence of thymosins β4, β4 sulfoxide, and β10 in bronchoalveolar lavage fluid of scleroderma patients with interstitial lung disease and the relation of these factors with pulmonary functional and radiological parameters.
Adult
Aged
Bronchoalveolar Lavage Fluid
Case-Control Studies
Chromatography, High Pressure Liquid
Chromatography, Reverse-Phase
Female
Follow-Up Studies
Humans
Lung
Lung Diseases, Interstitial
Male
Middle Aged
Odds Ratio
Pulmonary Diffusing Capacity
Rome
Scleroderma, Systemic
Spectrometry, Mass, Electrospray Ionization
Thymosin
Time Factors
Tomography, X-Ray Computed
Vital Capacity
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11699/68434
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus ND
  • ???jsp.display-item.citation.isi??? ND
social impact