Sfoglia per Rivista SCIENCE TRANSLATIONAL MEDICINE
A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease
2016-01-01 Scott, Ra; Freitag, Df; Li, L; Chu, Ay; Surendran, P; Young, R; Grarup, N; Stancakova, A; Chen, Yn; Varga, Tv; Yaghootkar, H; Luan, Ja; Zhao, Jh; Willems, Sm; Wessel, J; Wang, S; Maruthur, N; Michailidou, K; Pirie, A; van der Lee, Sj; Gillson, C; Al Olama, Aa; Amouyel, P; Arriola, L; Arveiler, D; Aviles-Olmos, I; Balkau, B; Barricarte, A; Barroso, I; Garcia, Sb; Bis, Jc; Blankenberg, S; Boehnke, M; Boeing, H; Boerwinkle, E; Borecki, Ib; Bork-Jensen, J; Bowden, S; Caldas, C; Caslake, M; Cupples, La; Cruchaga, C; Czajkowski, J; den Hoed, M; Dunn, Ja; Earl, Hm; Ehret, Gb; Ferrannini, E; Ferrieres, J; Foltynie, T; Ford, I; Forouhi, Ng; Gianfagna, F; Gonzalez, C; Grioni, S; Hiller, L; Jansson, Jh; Jorgensen, Me; Jukema, Jw; Kaaks, R; Kee, F; Kerrison, Nd; Key, Tj; Kontto, J; Kote-Jarai, Z; Kraja, At; Kuulasmaa, K; Kuusisto, J; Linneberg, A; Liu, Cy; Marenne, G; Mohlke, Kl; Morris, Ap; Muir, K; Muller-Nurasyid, M; Munroe, Pb; Navarro, C; Nielsen, Sf; Nilsson, Pm; Nordestgaard, Bg; Packard, Cj; Palli, D; Panico, S; Peloso, Gm; Perola, M; Peters, A; Poole, Cj; Quiros, Jr; Rolandsson, O; Sacerdote, C; Salomaa, V; Sanchez, Mj; Sattar, N; Sharp, Sj; Sims, R; Slimani, N; Smith, Ja; Thompson, Dj; Trompet, S; Tumino, R; van der, A DL; van der Schouw, Yt; Virtamo, J; Walker, M; Walter, K; Abraham, Je; Amundadottir, Lt; Aponte, Jl; Butterworth, A; Dupuis, J; Easton, Df; Eeles, Ra; Erdmann, J; Franks, Pw; Frayling, Tm; Hansen, T; Howson, Jmm; Jorgensen, T; Kooner, J; Laakso, M; Langenberg, C; Mccarthy, Mi; Pankow, Js; Pedersen, O; Riboli, E; Rotter, Ji; Saleheen, D; Samani, Nj; Schunkert, H; Vollenweider, P; O'Rahilly, S; Deloukas, P; Danesh, J; Goodarzi, Mo; Kathiresan, S; Meigs, Jb; Ehm, Mg; Wareham, Nj; Waterworth, Dm
Activation of ERBB2 signaling causes resistance to the EGFR-directed therapeutic antibody cetuximab
2011-01-01 Yonesaka, K.; Zejnullahu, K.; Okamoto, I.; Satoh, T.; Cappuzzo, F.; Souglakos, J.; Ercan, D.; Rogers, A.; Roncalli, M.; Takeda, M.; Fujisaka, Y.; Philips, J.; Shimuzu, T.; Maenishi, O.; Cho, Y.; Sun, J.; Destro, A.; Taira, K.; Takeda, K.; Okabe, T.; Swanson, J.; Itoh, H.; Takada, M.; Lifshits, E.; Okuno, K.; Angelman, J. A.; Shivdasani, R. A.; Nishio, K.; Fukuoka, M.; Varella-Garcia, M.; Nakagawa, K.; Janne, P. A.
Agrin induces long-term osteochondral regeneration by supporting repair morphogenesis
2020-01-01 Eldridge, Suzanne E; Barawi, Aida; Wang, Hui; Roelofs, Anke J; Kaneva, Magdalena; Guan, Zeyu; Lydon, Helen; Thomas, Bethan L; Thorup, Anne-Sophie; Fernandez, Beatriz F; Caxaria, Sara; Strachan, Danielle; Ali, Ahmed; Shanmuganathan, Kanatheepan; Pitzalis, Costantino; Whiteford, James R; Henson, Frances; Mccaskie, Andrew W; De Bari, Cosimo; Dell'Accio, Francesco
Bacteria-induced gap junctions in tumors favor antigen cross-presentation and antitumor immunity
2010-01-01 Saccheri, F.; Pozzi, C.; Avogadri, F.; Barozzi, S.; Faretta, M.; Fusi, P.; Rescigno, M.
Genomic instability analysis in DNA from Papanicolaou test provides proof-of-principle early diagnosis of high-grade serous ovarian cancer
2023-01-01 Paracchini, Lara; Mannarino, Laura; Romualdi, Chiara; Zadro, Riccardo; Beltrame, Luca; Fuso Nerini, Ilaria; Zola, Paolo; Laudani, Maria E; Pagano, Eva; Giordano, Livia; Fruscio, Robert; Landoni, Fabio; Franceschi, Silvia; Dalessandro, Maria L; Canzonieri, Vincenzo; Bocciolone, Luca; Lorusso, Domenica; Bosetti, Cristina; Raspagliesi, Francesco; Garassino, Isabella M G; D'Incalci, Maurizio; Marchini, Sergio
High-dose Vitamin C enhances cancer immunotherapy
2020-01-01 Magri, A.; Germano, G.; Lorenzato, A.; Lamba, S.; Chila, R.; Montone, M.; Amodio, V.; Ceruti, T.; Sassi, F.; Arena, S.; Abrignani, S.; D'Incalci, M.; Zucchetti, M.; Di Nicolantonio, F.; Bardelli, A.; co-last and corresponding, Authors
Mitochondrial metabolic reprogramming controls the induction of immunogenic cell death and efficacy of chemotherapy in bladder cancer
2021-01-01 Oresta, Bianca; Pozzi, Chiara; Braga, Daniele; Hurle, Rodolfo; Lazzeri, Massimo; Colombo, Piergiuseppe; Frego, Nicola; Erreni, Marco; Faccani, Cristina; Elefante, Grazia; Barcella, Matteo; Guazzoni, Giorgio; Rescigno, Maria
Mutations in the vesicular trafficking protein annexin A11 are associated with amyotrophic lateral sclerosis
2017-01-01 Smith, Bn; Topp, Sd; Fallini, C; Shibata, H; Chen, Hj; Troakes, C; King, A; Ticozzi, N; Kenna, Kp; Soragia-Gkazi, A; Miller, Jw; Sato, A; Dias, Dm; Jeon, M; Vance, C; Wong, Ch; de Majo, M; Kattuah, W; Mitchell, Jc; Scotter, El; Parkin, Nw; Sapp, Pc; Nolan, M; Nestor, Pj; Simpson, M; Weale, M; Lek, M; Baas, F; de Jong, Jmv; ten Asbroek, Alma; Redondo, Ag; Esteban-Perez, J; Tiloca, C; Verde, F; Duga, S; Leigh, N; Pall, H; Morrison, Ke; Al-Chalabi, A; Shaw, Pj; Kirby, J; Turner, Mr; Talbot, K; Hardiman, O; Glass, Jd; de Belleroche, J; Maki, M; Moss, Se; Miller, C; Gellera, C; Ratti, A; Al-Sarraj, S; Brown, Rh; Silani, V; Landers, Je; Shaw, Ce
A patient-based model of RNA mis-splicing uncovers treatment targets in Parkinson's disease
2020-01-01 Boussaad, I; Obermaier, Cd; Hanss, Z; Bobbili, Dr; Bolognin, S; Glaab, E; Wołyńska, K; Weisschuh, N; De Conti, L; May, C; Giesert, F; Grossmann, D; Lambert, A; Kirchen, S; Biryukov, M; Burbulla, Lf; Massart, F; Bohler, J; Cruciani, G; Schmid, B; Kurz-Drexler, A; May, P; Duga, S; Klein, C; Schwamborn, Jc; Marcus, K; Woitalla, D; Vogt Weisenhorn, Dm; Wurst, W; Baralle, M; Krainc, D; Gasser, T; Wissinger, B; Krüger, R
Sex-specific effects of daily tadalafil on diabetic heart kinetics in RECOGITO, a randomized, double-blind, placebo-controlled trial
2022-01-01 Pofi, Riccardo; Giannetta, Elisa; Feola, Tiziana; Galea, Nicola; Barbagallo, Federica; Campolo, Federica; Badagliacca, Roberto; Barbano, Biagio; Ciolina, Federica; Defeudis, Giuseppe; Filardi, Tiziana; Sesti, Franz; Minnetti, Marianna; Vizza, Carmine D; Pasqualetti, Patrizio; Caboni, Pierluigi; Carbone, Iacopo; Francone, Marco; Catalano, Carlo; Pozzilli, Paolo; Lenzi, Andrea; Venneri, Mary Anna; Gianfrilli, Daniele; Isidori, Andrea M
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease | 1-gen-2016 | Scott, Ra; Freitag, Df; Li, L; Chu, Ay; Surendran, P; Young, R; Grarup, N; Stancakova, A; Chen, Yn; Varga, Tv; Yaghootkar, H; Luan, Ja; Zhao, Jh; Willems, Sm; Wessel, J; Wang, S; Maruthur, N; Michailidou, K; Pirie, A; van der Lee, Sj; Gillson, C; Al Olama, Aa; Amouyel, P; Arriola, L; Arveiler, D; Aviles-Olmos, I; Balkau, B; Barricarte, A; Barroso, I; Garcia, Sb; Bis, Jc; Blankenberg, S; Boehnke, M; Boeing, H; Boerwinkle, E; Borecki, Ib; Bork-Jensen, J; Bowden, S; Caldas, C; Caslake, M; Cupples, La; Cruchaga, C; Czajkowski, J; den Hoed, M; Dunn, Ja; Earl, Hm; Ehret, Gb; Ferrannini, E; Ferrieres, J; Foltynie, T; Ford, I; Forouhi, Ng; Gianfagna, F; Gonzalez, C; Grioni, S; Hiller, L; Jansson, Jh; Jorgensen, Me; Jukema, Jw; Kaaks, R; Kee, F; Kerrison, Nd; Key, Tj; Kontto, J; Kote-Jarai, Z; Kraja, At; Kuulasmaa, K; Kuusisto, J; Linneberg, A; Liu, Cy; Marenne, G; Mohlke, Kl; Morris, Ap; Muir, K; Muller-Nurasyid, M; Munroe, Pb; Navarro, C; Nielsen, Sf; Nilsson, Pm; Nordestgaard, Bg; Packard, Cj; Palli, D; Panico, S; Peloso, Gm; Perola, M; Peters, A; Poole, Cj; Quiros, Jr; Rolandsson, O; Sacerdote, C; Salomaa, V; Sanchez, Mj; Sattar, N; Sharp, Sj; Sims, R; Slimani, N; Smith, Ja; Thompson, Dj; Trompet, S; Tumino, R; van der, A DL; van der Schouw, Yt; Virtamo, J; Walker, M; Walter, K; Abraham, Je; Amundadottir, Lt; Aponte, Jl; Butterworth, A; Dupuis, J; Easton, Df; Eeles, Ra; Erdmann, J; Franks, Pw; Frayling, Tm; Hansen, T; Howson, Jmm; Jorgensen, T; Kooner, J; Laakso, M; Langenberg, C; Mccarthy, Mi; Pankow, Js; Pedersen, O; Riboli, E; Rotter, Ji; Saleheen, D; Samani, Nj; Schunkert, H; Vollenweider, P; O'Rahilly, S; Deloukas, P; Danesh, J; Goodarzi, Mo; Kathiresan, S; Meigs, Jb; Ehm, Mg; Wareham, Nj; Waterworth, Dm | |
| Activation of ERBB2 signaling causes resistance to the EGFR-directed therapeutic antibody cetuximab | 1-gen-2011 | Yonesaka, K.; Zejnullahu, K.; Okamoto, I.; Satoh, T.; Cappuzzo, F.; Souglakos, J.; Ercan, D.; Rogers, A.; Roncalli, M.; Takeda, M.; Fujisaka, Y.; Philips, J.; Shimuzu, T.; Maenishi, O.; Cho, Y.; Sun, J.; Destro, A.; Taira, K.; Takeda, K.; Okabe, T.; Swanson, J.; Itoh, H.; Takada, M.; Lifshits, E.; Okuno, K.; Angelman, J. A.; Shivdasani, R. A.; Nishio, K.; Fukuoka, M.; Varella-Garcia, M.; Nakagawa, K.; Janne, P. A. | |
| Agrin induces long-term osteochondral regeneration by supporting repair morphogenesis | 1-gen-2020 | Eldridge, Suzanne E; Barawi, Aida; Wang, Hui; Roelofs, Anke J; Kaneva, Magdalena; Guan, Zeyu; Lydon, Helen; Thomas, Bethan L; Thorup, Anne-Sophie; Fernandez, Beatriz F; Caxaria, Sara; Strachan, Danielle; Ali, Ahmed; Shanmuganathan, Kanatheepan; Pitzalis, Costantino; Whiteford, James R; Henson, Frances; Mccaskie, Andrew W; De Bari, Cosimo; Dell'Accio, Francesco | |
| Bacteria-induced gap junctions in tumors favor antigen cross-presentation and antitumor immunity | 1-gen-2010 | Saccheri, F.; Pozzi, C.; Avogadri, F.; Barozzi, S.; Faretta, M.; Fusi, P.; Rescigno, M. | |
| Genomic instability analysis in DNA from Papanicolaou test provides proof-of-principle early diagnosis of high-grade serous ovarian cancer | 1-gen-2023 | Paracchini, Lara; Mannarino, Laura; Romualdi, Chiara; Zadro, Riccardo; Beltrame, Luca; Fuso Nerini, Ilaria; Zola, Paolo; Laudani, Maria E; Pagano, Eva; Giordano, Livia; Fruscio, Robert; Landoni, Fabio; Franceschi, Silvia; Dalessandro, Maria L; Canzonieri, Vincenzo; Bocciolone, Luca; Lorusso, Domenica; Bosetti, Cristina; Raspagliesi, Francesco; Garassino, Isabella M G; D'Incalci, Maurizio; Marchini, Sergio | |
| High-dose Vitamin C enhances cancer immunotherapy | 1-gen-2020 | Magri, A.; Germano, G.; Lorenzato, A.; Lamba, S.; Chila, R.; Montone, M.; Amodio, V.; Ceruti, T.; Sassi, F.; Arena, S.; Abrignani, S.; D'Incalci, M.; Zucchetti, M.; Di Nicolantonio, F.; Bardelli, A.; co-last and corresponding, Authors | |
| Mitochondrial metabolic reprogramming controls the induction of immunogenic cell death and efficacy of chemotherapy in bladder cancer | 1-gen-2021 | Oresta, Bianca; Pozzi, Chiara; Braga, Daniele; Hurle, Rodolfo; Lazzeri, Massimo; Colombo, Piergiuseppe; Frego, Nicola; Erreni, Marco; Faccani, Cristina; Elefante, Grazia; Barcella, Matteo; Guazzoni, Giorgio; Rescigno, Maria | |
| Mutations in the vesicular trafficking protein annexin A11 are associated with amyotrophic lateral sclerosis | 1-gen-2017 | Smith, Bn; Topp, Sd; Fallini, C; Shibata, H; Chen, Hj; Troakes, C; King, A; Ticozzi, N; Kenna, Kp; Soragia-Gkazi, A; Miller, Jw; Sato, A; Dias, Dm; Jeon, M; Vance, C; Wong, Ch; de Majo, M; Kattuah, W; Mitchell, Jc; Scotter, El; Parkin, Nw; Sapp, Pc; Nolan, M; Nestor, Pj; Simpson, M; Weale, M; Lek, M; Baas, F; de Jong, Jmv; ten Asbroek, Alma; Redondo, Ag; Esteban-Perez, J; Tiloca, C; Verde, F; Duga, S; Leigh, N; Pall, H; Morrison, Ke; Al-Chalabi, A; Shaw, Pj; Kirby, J; Turner, Mr; Talbot, K; Hardiman, O; Glass, Jd; de Belleroche, J; Maki, M; Moss, Se; Miller, C; Gellera, C; Ratti, A; Al-Sarraj, S; Brown, Rh; Silani, V; Landers, Je; Shaw, Ce | |
| A patient-based model of RNA mis-splicing uncovers treatment targets in Parkinson's disease | 1-gen-2020 | Boussaad, I; Obermaier, Cd; Hanss, Z; Bobbili, Dr; Bolognin, S; Glaab, E; Wołyńska, K; Weisschuh, N; De Conti, L; May, C; Giesert, F; Grossmann, D; Lambert, A; Kirchen, S; Biryukov, M; Burbulla, Lf; Massart, F; Bohler, J; Cruciani, G; Schmid, B; Kurz-Drexler, A; May, P; Duga, S; Klein, C; Schwamborn, Jc; Marcus, K; Woitalla, D; Vogt Weisenhorn, Dm; Wurst, W; Baralle, M; Krainc, D; Gasser, T; Wissinger, B; Krüger, R | |
| Sex-specific effects of daily tadalafil on diabetic heart kinetics in RECOGITO, a randomized, double-blind, placebo-controlled trial | 1-gen-2022 | Pofi, Riccardo; Giannetta, Elisa; Feola, Tiziana; Galea, Nicola; Barbagallo, Federica; Campolo, Federica; Badagliacca, Roberto; Barbano, Biagio; Ciolina, Federica; Defeudis, Giuseppe; Filardi, Tiziana; Sesti, Franz; Minnetti, Marianna; Vizza, Carmine D; Pasqualetti, Patrizio; Caboni, Pierluigi; Carbone, Iacopo; Francone, Marco; Catalano, Carlo; Pozzilli, Paolo; Lenzi, Andrea; Venneri, Mary Anna; Gianfrilli, Daniele; Isidori, Andrea M |
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