| Nome |
# |
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Efficacy and safety of dupilumab in patients with severe chronic rhinosinusitis with nasal polyps (LIBERTY NP SINUS-24 and LIBERTY NP SINUS-52): results from two multicentre, randomised, double-blind, placebo-controlled, parallel-group phase 3 trials, file de164a8f-1ca7-73f5-e053-d805fe0a7be4
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385
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Efficacy of Trunk Balance Exercises for Individuals With Chronic Low Back Pain: A Randomized Clinical Trial, file de164a8e-c4f6-73f5-e053-d805fe0a7be4
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354
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|
Minimal morphological criteria for defining bone marrow dysplasia: a basis for clinical implementation of WHO classification of myelodysplastic syndromes, file de164a8f-350c-73f5-e053-d805fe0a7be4
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211
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Type 2 Inflammation in Eosinophilic Esophagitis: From Pathophysiology to Therapeutic Targets, file 75643d7a-adcd-4266-9220-52d79c75b3e4
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170
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Patient-ventilator asynchrony in adult critically ill patients, file 8c74953d-35df-445c-b03b-bd3a3cd381c5
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157
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Cholangiocarcinoma Stem-like Subset Shapes Tumor-initiating Niche by Educating Associated Macrophages, file de164a8f-350e-73f5-e053-d805fe0a7be4
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126
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|
Healthcare organizational performance: why changing the culture really matters. Commentary, file de164a8f-1bde-73f5-e053-d805fe0a7be4
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121
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Multimodality imaging of adult rhabdomyosarcoma: the added value of hybrid imaging, file de164a8f-1019-73f5-e053-d805fe0a7be4
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119
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|
Assessment of Fluid Responsiveness in Prone Neurosurgical Patients Undergoing Protective Ventilation: Role of Dynamic Indices, Tidal Volume Challenge, and End-Expiratory Occlusion Test, file 1d7a39a2-d35c-4fa8-8aa8-2fc5b8543ed5
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117
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Effectiveness of a national quality improvement programme to improve survival after emergency abdominal surgery (EPOCH): a stepped-wedge cluster-randomised trial, file de164a8f-323d-73f5-e053-d805fe0a7be4
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113
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How can assessing hemodynamics help to assess volume status?, file 0ee31562-09ff-4193-a388-bce3f9a79a10
|
108
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Invasive arterial pressure monitoring: much more than mean arterial pressure!, file ac106e2e-7e0b-4060-9d24-f7a84b124dad
|
104
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|
Ten answers to key questions for fluid management in intensive care, file d9ec839e-ef48-4647-9fe0-7d049c091620
|
97
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The Microglial Innate Immune Receptor TREM2 Is Required for Synapse Elimination and Normal Brain Connectivity., file de164a8e-c674-73f5-e053-d805fe0a7be4
|
93
|
|
Tidal volume challenge to predict fluid responsiveness in the operating room An observational study, file 13db7283-04f4-436f-90e8-c579c61a87b4
|
91
|
|
Single inhaler extrafine triple therapy in uncontrolled asthma (TRIMARAN and TRIGGER): two double-blind, parallel-group, randomised, controlled phase 3 trials, file de164a8f-1d19-73f5-e053-d805fe0a7be4
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89
|
|
Continuous Glucose Monitoring (CGM) Adherence in Youth With Type 1 Diabetes: Associations With Biomedical and Psychosocial Variables, file de164a8f-33bb-73f5-e053-d805fe0a7be4
|
85
|
|
State-of-the-art of FAPI-PET imaging: a systematic review and meta-analysis, file de164a8f-2d35-73f5-e053-d805fe0a7be4
|
84
|
|
Is R1 vascular hepatectomy for hepatocellular carcinoma oncologically adequate? Analysis of 327 consecutive patients, file de164a8f-2e75-73f5-e053-d805fe0a7be4
|
81
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Observational Study of PD-L1, TGF-β, and Immune Cell Infiltrates in Hepatocellular Carcinoma, file 9b02cf8c-ef0f-45a2-b611-eff6a673dd80
|
79
|
|
Mini fluid chAllenge aNd End-expiratory occlusion test to assess flUid responsiVEness in the opeRating room (MANEUVER study): A multicentre cohort study, file 5d5850d1-7e7a-408e-af9a-11b25188acca
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74
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Minimally Invasive versus Open Distal Pancreatectomy for Ductal Adenocarcinoma (DIPLOMA), file ec10ae60-da82-42e2-875e-010b8fcfe5bb
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73
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A Combined Approach Employing Chlorotoxin-Nanovectors and Low Dose Radiation To Reach Infiltrating Tumor Niches in Glioblastoma., file de164a8e-bb96-73f5-e053-d805fe0a7be4
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67
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Elective Cancer Surgery in COVID-19-Free Surgical Pathways During the SARS-CoV-2 Pandemic: An International, Multicenter, Comparative Cohort Study, file 1f38b747-99f6-45a1-a2cf-e92c572e8ae1
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65
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Action observation training to improve motor function recovery: a systematic review, file de164a8e-c0e2-73f5-e053-d805fe0a7be4
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64
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|
Cardiac cycle efficiency and dicrotic pressure variations: new parameters for fluid therapy: An observational study, file 0529e72d-0411-410a-bb8e-2a633061c9f0
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62
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Is supratotal resection achievable in low-grade gliomas? Feasibility, putative factors, safety, and functional outcome., file de164a8f-08ac-73f5-e053-d805fe0a7be4
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62
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Prognostic factors in patients with metastatic germ cell tumors who experienced treatment failure with cisplatin-based first-line chemotherapy, file de164a8f-133c-73f5-e053-d805fe0a7be4
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59
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Clinical Outcomes of Castration-resistant Prostate Cancer Treatments Administered as Third or Fourth Line Following Failure of Docetaxel and Other Second-line Treatment: Results of an Italian Multicentre Study, file 139201cd-fc1d-4c43-a812-ae076129e6c6
|
54
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Activation of the VEGFC/VEGFR3 Pathway Induces Tumor Immune Escape in Colorectal Cancer, file de164a8e-c0e9-73f5-e053-d805fe0a7be4
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54
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Ustekinumab for patients with primary biliary cholangitis who have an inadequate response to ursodeoxycholic acid : a proof-of-concept study, file ee7cd394-a348-4f2a-8327-2857ea296af1
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52
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Genetic screening of Anderson-Fabry disease in probands referred from multispecialty clinics, file de164a8e-c2e9-73f5-e053-d805fe0a7be4
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51
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Identification of Endpoints for Development of Antifibrosis Drugs for Treatment of Crohn's Disease, file de164a8e-c658-73f5-e053-d805fe0a7be4
|
49
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Alexithymia, responsibility attitudes and suicide ideation among outpatients with obsessive-compulsive disorder: An exploratory study, file bf3a2f8d-1dc8-413c-addf-e7eb37fa8b34
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47
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|
Preoperative Biliary Stenting and Major Morbidity After Pancreatoduodenectomy: Does Elapsed Time Matter? The FRAGERITA Study Group, file 63e5032c-5886-407e-b33c-8ca14e44d7cc
|
46
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|
Pancreatic Neuroendocrine Tumours: The Role of Endoscopic Ultrasound Biopsy in Diagnosis and Grading Based on the WHO 2017 Classification, file de164a8f-2335-73f5-e053-d805fe0a7be4
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46
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Innate immunity, inflammation and tumour progression: double-edged swords, file de164a8f-34a3-73f5-e053-d805fe0a7be4
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45
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Occurrence and significance of tumor - Associated neutrophils in patients with colorectal cancer, file de164a8f-2430-73f5-e053-d805fe0a7be4
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42
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Determination of CA 19-9 antigen in serum and pancreatic juice for differential diagnosis of pancreatic adenocarcinoma from chronic pancreatitis., file de164a8f-254a-73f5-e053-d805fe0a7be4
|
42
|
|
Precision Oncology in Lower-Grade Gliomas: Promises and Pitfalls of Therapeutic Strategies Targeting IDH-Mutations, file 4b7ba300-eb07-422b-b443-10cc19f2cfa1
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40
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Discordance Among Pathologists in the United States and Europe in Diagnosis of Low-Grade Dysplasia for Patients With Barrett's Esophagus, file 647a887d-8ae9-4b3c-b8c0-00edc1937a1b
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39
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Control of inducible gene expression links cohesin to hematopoietic progenitor self-renewal and differentiation, file 4d0a9e45-c77b-428a-b469-5317994009f4
|
38
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|
Rehabilitation that incorporated virtual reality is more effective for improving walking speed, balance and mobility after stroke: a systematic review, file de164a8e-bd69-73f5-e053-d805fe0a7be4
|
38
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Dynamic Computed Tomography Myocardial Perfusion Imaging, file bc3b9ce7-4699-4ca5-967f-919b502bcdef
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37
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|
Review article: anti TNF-alpha induced psoriasis in patients with inflammatory bowel disease, file de164a8f-2e50-73f5-e053-d805fe0a7be4
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37
|
|
TNM 8th edition in thyroid cancer staging: is there an improvement in predicting recurrence?, file de164a8f-3773-73f5-e053-d805fe0a7be4
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37
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|
Serous cystic neoplasm of the pancreas: a multinational study of 2622 patients under the auspices of the International Association of Pancreatology and European Pancreatic Club (European Study Group on Cystic Tumors of the Pancreas), file 0bf8bcf3-88eb-4427-8f27-f568d67d4b48
|
36
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Complement activation promoted by the lectin pathway mediates C3aR-dependent sarcoma progression and immunosuppression, file de164a8f-35a2-73f5-e053-d805fe0a7be4
|
34
|
|
Association between use of enhanced recovery after surgery protocols and postoperative complications in colorectal surgery in Europe: The EuroPOWER international observational study, file b5f7a80e-1f6d-4531-b6fc-98ac1c516934
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33
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Robot-assisted Surgery for Benign Ureteral Strictures: Experience and Outcomes from Four Tertiary Care Institutions, file de164a8e-d95b-73f5-e053-d805fe0a7be4
|
32
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|
Phase I/Ib Clinical Trial of Sabatolimab, an Anti-TIM-3 Antibody, Alone and in Combination with Spartalizumab, an Anti-PD-1 Antibody, in Advanced Solid Tumors, file de164a8f-2f0c-73f5-e053-d805fe0a7be4
|
32
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|
Conservative Treatment and Percutaneous Pain Relief Techniques in Patients with Lumbar Spinal Stenosis: WFNS Spine Committee Recommendations, file de164a8f-30a8-73f5-e053-d805fe0a7be4
|
32
|
|
Uncommon single and compound EGFR mutations: clinical outcomes of a heterogeneous subgroup of NSCLC, file de164a8f-3372-73f5-e053-d805fe0a7be4
|
32
|
|
Multivariable haemodynamic approach to predict the fluid challenge response: A multicentre cohort study, file 71b6c131-976c-45fe-8f6f-f51a08c716ab
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31
|
|
Co-optation of Tandem DNA Repeats for the Maintenance of Mesenchymal Identity, file 80967a39-51b1-4482-a7fc-13e0aa648bcd
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31
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A microRNA code for prostate cancer metastasis, file de164a8e-c666-73f5-e053-d805fe0a7be4
|
31
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Clinical similarity of biosimilar ABP 501 to adalimumab in the treatment of patients with moderate to severe plaque psoriasis: A randomized, double-blind, multicenter, phase III study, file de164a8f-2ca6-73f5-e053-d805fe0a7be4
|
30
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Variant discovery in patients with Mendelian vascular anomalies by next-generation sequencing and their use in patient clinical management, file de164a8f-3c2f-73f5-e053-d805fe0a7be4
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30
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|
Temozolomide treatment alters mismatch repair and boosts mutational burden in tumor and blood of colorectal cancer patients, file f4249dd0-7991-4122-a93c-70dba5a8fa14
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29
|
|
Interleukins 4 and 13 in Asthma: Key Pathophysiologic Cytokines and Druggable Molecular Targets, file 78e7b7da-1419-411c-9994-cbbca3d80f9d
|
28
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Myositis-specific autoantibodies and their association with malignancy in Italian patients with polymyositis and dermatomyositis, file d9da1501-871b-4f67-9dcf-a8c017c8d00f
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28
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|
Neurosurgical Digital Teaching in Low-Middle Income Countries: Beyond the Frontiers of Traditional Education, file de164a8e-c439-73f5-e053-d805fe0a7be4
|
28
|
|
Nivolumab for relapsed/refractory classic Hodgkin lymphoma after failure of autologous hematopoietic cell transplantation: extended follow-up of the multicohort single-arm phase II CheckMate 205 trial, file de164a8e-c681-73f5-e053-d805fe0a7be4
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28
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|
Gemcitabine with or without ramucirumab as second-line treatment for malignant pleural mesothelioma (RAMES): a randomised, double-blind, placebo-controlled, phase 2 trial, file de164a8f-282b-73f5-e053-d805fe0a7be4
|
28
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|
IL-1R8 is a checkpoint in NK cells regulating anti-tumour and anti-viral activity, file de164a8f-3276-73f5-e053-d805fe0a7be4
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28
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|
Esophageal pressure versus gas exchange to set peep during intraoperative ventilation, file 076ab6a7-0a9a-4daf-a209-007cd2030c0f
|
27
|
|
A Clinically-Translatable Machine Learning Algorithm for the Prediction of Alzheimer's Disease Conversion in Individuals with Mild and Premild Cognitive Impairment, file 1670314b-dbd7-4e4f-9f89-8171146a23ca
|
27
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|
Development and Validation of a Scoring System to Predict Outcomes of Patients With Primary Biliary Cirrhosis Receiving Ursodeoxycholic Acid Therapy, file a7df489f-bca0-4d3c-9c1f-093488330c92
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27
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|
Management of germ cell tumors during the outbreak of the novel coronavirus disease‐19 pandemic: a survey of international expertise centers, file de164a8f-1321-73f5-e053-d805fe0a7be4
|
27
|
|
Autologous Cell Therapy Approach for Duchenne Muscular Dystrophy using PiggyBac Transposons and Mesoangioblasts, file de164a8f-34ba-73f5-e053-d805fe0a7be4
|
27
|
|
Post-operative analgesia following total knee arthroplasty: comparison of low-dose intrathecal morphine and single-shot ultrasound-guided femoral nerve block: a randomized, single blinded, controlled study, file d199b9c6-f9bf-45b8-ba98-033cfc8d019e
|
26
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|
Opposing macrophage polarization programs show extensive epigenomic and transcriptional cross-talk, file d59e9538-84df-4e38-a427-0f115f4f43d8
|
26
|
|
Generating Neuronal Diversity in the Mammalian Cerebral Cortex, file de164a8e-cff6-73f5-e053-d805fe0a7be4
|
26
|
|
Pentraxins in the activation and regulation of innate immunity, file de164a8f-2a7c-73f5-e053-d805fe0a7be4
|
26
|
|
Periendoscopic management of direct oral anticoagulants: a prospective cohort study, file 80870680-e8fe-48b0-b4ef-772357e7101a
|
25
|
|
Activity and safety of ceritinib in patients with ALK-rearranged non-small-cell lung cancer(ASCEND-1): update results from the multicenter, open-label, phase 1 trial., file de164a8e-c48f-73f5-e053-d805fe0a7be4
|
25
|
|
Subjectivity as an emergent property of information processing by neuronal networks, file de164a8f-061b-73f5-e053-d805fe0a7be4
|
25
|
|
MicroRNA-425-3p predicts response to sorafenib therapy in patients with hepatocellular carcinoma, file de164a8f-1025-73f5-e053-d805fe0a7be4
|
25
|
|
Brain Structural and Functional Connectivity in Parkinson’s Disease With Freezing of Gait, file de164a8e-bd68-73f5-e053-d805fe0a7be4
|
24
|
|
Decompressive Surgery for Lumbar Spinal Stenosis: WFNS Spine Committee Recommendations, file de164a8f-352b-73f5-e053-d805fe0a7be4
|
24
|
|
Preservation of Axillary Lymph Nodes Compared with Complete Dissection in T1-2 Breast Cancer Patients Presenting One or Two Metastatic Sentinel Lymph Nodes: The SINODAR-ONE Multicenter Randomized Clinical Trial, file d4238a46-c7db-4b9b-a89f-eb83bc2330ec
|
23
|
|
Combined genetic deletion of Th2 cytokines does not affect ischemic injury in mice, file de164a8f-23e2-73f5-e053-d805fe0a7be4
|
23
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|
A Natural Language Processing-Based Virtual Patient Simulator and Intelligent Tutoring System for the Clinical Diagnostic Process: Simulator Development and Case Study, file de164a8f-257e-73f5-e053-d805fe0a7be4
|
23
|
|
Second-Line Tisagenlecleucel or Standard Care in Aggressive B-Cell Lymphoma, file 3eed5850-a570-4cb0-a3d6-8b8d3c830ac8
|
22
|
|
Long-Term Survival Following Multivessel Revascularization in Patients With Diabetes: The FREEDOM Follow-On Study., file 6adc9661-06d3-4059-841a-aab7e416c04b
|
22
|
|
Trends in adult body-mass index in 200 countries from 1975 to 2014: a pooled analysis of 1698 population-based measurement studies with 19.2 million participants, file b1275f38-9902-4a9e-8991-4a6236ea6e31
|
22
|
|
Fluid Challenge During Anesthesia: A Systematic Review and Meta-analysis, file c739bee4-db81-4cea-8237-24ee2c389558
|
22
|
|
Longitudinal MRI quantification of muscle degeneration in Duchenne muscular dystrophy, file de164a8e-c014-73f5-e053-d805fe0a7be4
|
22
|
|
Influence of Pachymetry and Intraocular Pressure on Dynamic Corneal Response Parameters in Healthy Patients, file de164a8e-c07f-73f5-e053-d805fe0a7be4
|
22
|
|
Vascular endothelial growth factor C disrupts the endothelial lymphatic barrier to promote colorectal cancer invasion, file de164a8e-c169-73f5-e053-d805fe0a7be4
|
22
|
|
Lack of IL-1R8 in neurons causes hyperactivation of IL-1 receptor pathway and induces MECP2-dependent synaptic defects., file de164a8e-c0db-73f5-e053-d805fe0a7be4
|
21
|
|
PTX3 is an extrinsic oncosuppressor regulating complement-dependent inflammation in cancer, file de164a8f-327c-73f5-e053-d805fe0a7be4
|
21
|
|
Multimodal single-cell profiling of intrahepatic cholangiocarcinoma defines hyperactivated Tregs as a potential therapeutic target, file de3c4642-eb40-42be-aaa2-92daf1bf30f6
|
21
|
|
Very rapid improvement of extended nitric oxide parameters, associated with clinical and functional betterment, in patients with chronic rhinosinusitis with nasal polyps (CRSwNP) treated with Dupilumab, file 42e3d296-32fc-4863-8255-6e13e5458fd8
|
20
|
|
Comparison between 1.5 and 3.0 Tesla magnetic resonance enterography for the assessment of disease activity and complications in ileo-colonic Crohn's disease, file de164a8f-25cf-73f5-e053-d805fe0a7be4
|
20
|
|
Risks of breast and ovarian cancer for women harboring pathogenic missense variants in BRCA1 and BRCA2 compared with those harboring protein truncating variants, file de164a8f-3abf-73f5-e053-d805fe0a7be4
|
20
|
|
Association Between BNT162b2 Vaccination and Long COVID After Infections Not Requiring Hospitalization in Health Care Workers, file 5a682c93-8c45-4130-a71f-6adb73ecbd4f
|
19
|
|
The evolution of post-operative pancreatic fistula (POPF) classification: A single-center experience, file c27ec615-210a-4729-8a9b-a75856899c19
|
19
|
|
Stenting of the proximal colon in patients with malignant large bowel obstruction: techniques and outcomes, file de164a8f-2040-73f5-e053-d805fe0a7be4
|
19
|
|
Evolving notions on immune response in colorectal cancer and their implications for biomarker development, file de164a8f-24da-73f5-e053-d805fe0a7be4
|
19
|
| Totale |
5.494 |