Total marrow and lymph nodes irradiation in conditioning regimen for allogeneic hematopoietic stem cell transplantation Artificial Intelligence algorithms to automate the Total Marrow and Lymph-node Irradiation by VMAT optimization using WB-CT/MRI and synthetic WB-CT - The AutoMI project

Purpose/Objective The AuToMI project focuses on improving the TMLI clinical workflow and automating radiotherapy procedures through the application of Artificial Intelligence (AI). The primary goal is to streamline and enhance the efficiency of the radiotherapy treatment process by automating two critical steps: contouring of the target volumes and treatment plan optimization. In parallel, the project aims to integrate whole-body magnetic resonance imaging (WB-MRI) to improve the accuracy of ...

Total marrow and lymph nodes irradiation in conditioning regimen for allogeneic hematopoietic stem cell transplantation Artificial Intelligence algorithms to automate the Total Marrow and Lymph-node Irradiation by VMAT optimization using WB-CT/MRI and synthetic WB-CT - The AutoMI project

Purpose/Objective The AuToMI project focuses on improving the TMLI clinical workflow and automating radiotherapy procedures through the application of Artificial Intelligence (AI). The primary goal is to streamline and enhance the efficiency of the radiotherapy treatment process by automating two critical steps: contouring of the target volumes and treatment plan optimization. In parallel, the project aims to integrate whole-body magnetic resonance imaging (WB-MRI) to improve the accuracy of ...

Antibody-independent activation of complement and its regulation on multiple membrane layers of Plasmodium falciparum-infected erythrocytes

Malaria, caused by Plasmodium falciparum, remains a significant health burden, especially in tropical regions, as the parasite develops within human red blood cells (RBCs). The complement system initiates an early immune response against the parasite, but P. falciparum effectively evades complement-mediated killing. This study investigates how complement proteins deposit and are regulated on infected RBCs (iRBCs) and merozoites in the absence of parasite-specific antibodies. We show that fact...

Tailoring neuroradiological functional imaging and translational analysis strategies to optimize newly diagnosed GBM volume definition: enhancing surgical resection beyond enhancing boundaries