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Strong right-hand preference on the population level is a uniquely human feature, although the neural basis for this is still not clearly defined. Recent behavioural and neuroimaging literature suggests that hand preference may be related to the orchestrated function and size of fronto-parietal white matter tracts bilaterally. Lesions to these tracts induced during tumour resection may provide an opportunity to test this hypothesis. In the present study, a cohort of seventeen neurosurgical pa...
Despite the compelling clinical need to regenerate damaged tissues/organs, the impressive advances in the field of tissue engineering have yet to result in viable engineered tissue products with wide-spread therapeutic adoption. Manufacturing-related issues, including regulatory compliance, standardization, up-scaling, and cost-effectiveness, have been proposed as central challenges to be addressed for the commercial success of a cell-based engineered product. In fact, the central bioprocesse...
The main driving idea of the project is the creation of a conceptually new type of scaffolds able to be manipulated in situ by means of magnetic forces. This approach is expected to generate scaffolds with such characteristics as multiple use and possibly multipurpose delivery in order to repair large bone defects and osteochondral lesions in the articular surface of the skeletal system.
Tissue engineering (TE) is a rapidly emerging collection of technologies aimed at the regeneration of tissues and organs for the treatment of disease and injury. Whilst some success has already been achieved, demonstrating the potential for TE to make a significant impact on healthcare, there has been a marked lack of connectivity between the different components such that TE will not deliver this promise under current conditions. STEPS addresses this by introducing a systems approach to TE a...
SCAFFOLD PER LA RIGENERAZIONE DEI TESSUTI SCHELETRICI: VALUTAZIONE PRECLINICA DELLA LORO COMPATIBILITA’ ED EFFICIENZA
Lo sviluppo di sistemi per trattare patologie osteo-articolari presentano attualmente logiche significativamente innovative rispetto agli approcci convenzionali, estremamente invasivi. Tali sistemi mirano al rapido ripristino della funzionalità osteo-articolare, grazie all’impiego di materiali bioattivi, fattori di crescita e cellule. I nuovi biomateriali dovranno possedere sia buone proprietà meccaniche che capacità di rigenerazione tessutali. Nella realizzazione di questi materiali, l’appro...
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Data di pubblicazione
- 2010 - 201917
- 2001 - 20097
- bio-hybrid scaffold1
- Tissue Engineering1
Accesso al fulltext
- no fulltext24