The small intestine coordinates nutrient absorption and immune defense, but the epithelial signaling mechanisms bridging these functions are unclear. In this issue of Immunity, Yu et al. reveal a gasdermin-D-driven circuit that links lipid uptake and enterocyte metabolism to gamma delta T cell maintenance and barrier protection.
Gut instincts: Gasdermin D feeds while it fights
Brescia, Paola;Rescigno, Maria
2025-01-01
Abstract
The small intestine coordinates nutrient absorption and immune defense, but the epithelial signaling mechanisms bridging these functions are unclear. In this issue of Immunity, Yu et al. reveal a gasdermin-D-driven circuit that links lipid uptake and enterocyte metabolism to gamma delta T cell maintenance and barrier protection.File in questo prodotto:
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