Transforming growth factor beta (TGF-β) signalling is involved in the development of hepatocellular carcinoma (HCC). We followed changes in biomarkers during treatment of patients with HCC with the TGF-βRI/ALK5 inhibitor galunisertib.

Biomarkers and overall survival in patients with advanced hepatocellular carcinoma treated with TGF-βRI inhibitor galunisertib

Santoro, Armando;
2020-01-01

Abstract

Transforming growth factor beta (TGF-β) signalling is involved in the development of hepatocellular carcinoma (HCC). We followed changes in biomarkers during treatment of patients with HCC with the TGF-βRI/ALK5 inhibitor galunisertib.
2020
Adult
Aged
Aged, 80 and over
Antigens, CD
Biomarkers, Tumor
Cadherins
Carcinoma, Hepatocellular
Cohort Studies
Female
Humans
Liver Neoplasms
Male
MicroRNAs
Middle Aged
Prognosis
Pyrazoles
Quinolines
Receptor, Transforming Growth Factor-beta Type I
Survival Rate
Transforming Growth Factor beta1
Treatment Outcome
alpha-Fetoproteins
Adult
Aged
Aged, 80 and over
Antigens, CD
Biomarkers, Tumor
Cadherins
Carcinoma, Hepatocellular
Cohort Studies
Female
Humans
Liver Neoplasms
Male
MicroRNAs
Middle Aged
Prognosis
Pyrazoles
Quinolines
Receptor, Transforming Growth Factor-beta Type I
Survival Rate
Transforming Growth Factor beta1
Treatment Outcome
alpha-Fetoproteins
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11699/54858
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