Patients with cancer are at increased risk of complicated severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection, but it is still unclear if the risk of mortality is influenced by cancer type or ongoing anti-cancer treatments. An interesting debate concerning the potential relationship between androgen deprivation therapy (ADT) and SARS-CoV-2 infection has recently been opened in the case of prostate cancer (PC), and the aim of this multi-centre cohort study was to investigate the incidence and outcomes of SARS-CoV-2 infection in patients with metastatic castration-resistant prostrate cancer (mCRPC).

Incidence and outcomes of severe acute respiratory syndrome coronavirus 2 infection in patients with metastatic castration-resistant prostate cancer

Zucali, Paolo;
2020-01-01

Abstract

Patients with cancer are at increased risk of complicated severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection, but it is still unclear if the risk of mortality is influenced by cancer type or ongoing anti-cancer treatments. An interesting debate concerning the potential relationship between androgen deprivation therapy (ADT) and SARS-CoV-2 infection has recently been opened in the case of prostate cancer (PC), and the aim of this multi-centre cohort study was to investigate the incidence and outcomes of SARS-CoV-2 infection in patients with metastatic castration-resistant prostrate cancer (mCRPC).
2020
Androgen deprivation therapy
COVID-19
Metastatic castration-resistant prostate cancer
SARS-CoV-2 infection
Aged
Aged, 80 and over
Betacoronavirus
Bone Neoplasms
Combined Modality Therapy
Coronavirus Infections
Follow-Up Studies
Humans
Incidence
Italy
Male
Pandemics
Pneumonia, Viral
Prognosis
Prostatic Neoplasms, Castration-Resistant
Retrospective Studies
Survival Rate
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11699/55243
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