The antiproliferative effects of three synthetic analogs of aliphatic acetogenins selected from a previous screening were compared to those of the drugs used for the treatment of malignant pleural mesothelioma (MPM) and pancreatic ductal adenocarcinoma (PDAC).

Antiproliferative effects of novel aliphatic acetogenin analogs against aggressive solid tumor cell lines

Zucali, Paolo;
2011

Abstract

The antiproliferative effects of three synthetic analogs of aliphatic acetogenins selected from a previous screening were compared to those of the drugs used for the treatment of malignant pleural mesothelioma (MPM) and pancreatic ductal adenocarcinoma (PDAC).
Acetogenins
Adenocarcinoma
Apoptosis
Carcinoma, Pancreatic Ductal
Cell Cycle
Cell Line, Tumor
Cell Proliferation
Dose-Response Relationship, Drug
Drug Screening Assays, Antitumor
Enzyme-Linked Immunosorbent Assay
Flow Cytometry
Humans
Mesothelioma
Molecular Structure
Pancreatic Neoplasms
Phosphorylation
Pleural Neoplasms
Proto-Oncogene Proteins c-akt
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11699/55280
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