Significant efforts have been made to investigate the molecular pathways involved in thymic carcinogenesis. However, genetic findings have still not impacted clinical practice. The aim of this exploratory trial was to evaluate the immunoscore and molecular profile of a series of thymic carcinomas (TCs), correlating this data with clinical outcome.

Mutation profile and immunoscore signature in thymic carcinomas: An exploratory study and review of the literature

Asselta, Rosanna;Di Tommaso, Luca;Cardamone, Giulia;Santoro, Armando
;
Duga, Stefano;Zucali, Paolo Andrea
2021-01-01

Abstract

Significant efforts have been made to investigate the molecular pathways involved in thymic carcinogenesis. However, genetic findings have still not impacted clinical practice. The aim of this exploratory trial was to evaluate the immunoscore and molecular profile of a series of thymic carcinomas (TCs), correlating this data with clinical outcome.
2021
Germline mutation
immunoscore
next-generation sequencing
somatic mutation
thymic carcinoma
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11699/58909
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