The growth of gliomas depends on the balance of factors stimulating or inhibiting angiogenesis, tumor cell invasion and proliferation. The administration of endogenous inhibitors to experimental human gliomas in animal models resulted in a significant inhibition of tumor growth. It is becoming apparent that resistance can develop over time to many types of endogenous inhibitors and seems to be influenced by the tumor type and system of delivery.

Long-term inhibition of glioma growth by systemic administration of human PEX

Costa, F;
2003-01-01

Abstract

The growth of gliomas depends on the balance of factors stimulating or inhibiting angiogenesis, tumor cell invasion and proliferation. The administration of endogenous inhibitors to experimental human gliomas in animal models resulted in a significant inhibition of tumor growth. It is becoming apparent that resistance can develop over time to many types of endogenous inhibitors and seems to be influenced by the tumor type and system of delivery.
2003
Angiogenesis Inhibitors
Animals
Apoptosis
Blotting, Western
Cell Division
Disease Models, Animal
Endothelial Cells
Glioma
Humans
Male
Matrix Metalloproteinase 2
Mice
Mice, Nude
Neoplasm Transplantation
Peptide Fragments
Polymerase Chain Reaction
Recombinant Proteins
Time Factors
Tumor Cells, Cultured
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11699/61524
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