We investigated the HCV-RNA amount, variability and prevalence of resistance-associated substitutions (RASs), in plasma, hepatic tumoral and non-tumoral tissue samples in patients undergoing liver-transplant/hepatic-resection (LT/HR), because of hepatocellular carcinoma and/or cirrhosis.

HCV resistance compartmentalization within tumoral and non-tumoral liver in transplanted patients with hepatocellular carcinoma

Cento, Valeria;
2019-01-01

Abstract

We investigated the HCV-RNA amount, variability and prevalence of resistance-associated substitutions (RASs), in plasma, hepatic tumoral and non-tumoral tissue samples in patients undergoing liver-transplant/hepatic-resection (LT/HR), because of hepatocellular carcinoma and/or cirrhosis.
2019
Compartmentalization
HBV-coinfection
HCV
Hepatocellular carcinoma
Liver transplantation
Resistance-associated substitutions
Aged
Antiviral Agents
Carcinoma, Hepatocellular
Coinfection
Drug Resistance, Viral
Drug Therapy, Combination
Genotype
Hepacivirus
Hepatitis B, Chronic
Hepatitis C, Chronic
Humans
Liver Neoplasms
Male
Middle Aged
Phylogeny
Ribavirin
Sofosbuvir
Sustained Virologic Response
Treatment Failure
Viral Nonstructural Proteins
Liver Transplantation
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11699/65923
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