Patient outcomes are poor for aggressive B-cell non-Hodgkin's lymphomas not responding to or progressing within 12 months after first-line therapy. Tisagenlecleucel is an anti-CD19 chimeric antigen receptor T-cell therapy approved for diffuse large B-cell lymphoma after at least two treatment lines.

Second-Line Tisagenlecleucel or Standard Care in Aggressive B-Cell Lymphoma

Santoro, Armando;
2022-01-01

Abstract

Patient outcomes are poor for aggressive B-cell non-Hodgkin's lymphomas not responding to or progressing within 12 months after first-line therapy. Tisagenlecleucel is an anti-CD19 chimeric antigen receptor T-cell therapy approved for diffuse large B-cell lymphoma after at least two treatment lines.
2022
Inglese
386
7
629
639
11
Adult
Aged
Antineoplastic Agents, Immunological
Antineoplastic Combined Chemotherapy Protocols
Combined Modality Therapy
Female
Humans
Lymphoma, Large B-Cell, Diffuse
Male
Middle Aged
Progression-Free Survival
Receptors, Antigen, T-Cell
Receptors, Chimeric Antigen
Salvage Therapy
Transplantation, Autologous
Hematopoietic Stem Cell Transplantation
Immunotherapy, Adoptive
Bishop, Michael R; Dickinson, Michael; Purtill, Duncan; Barba, Pere; Santoro, Armando; Hamad, Nada; Kato, Koji; Sureda, Anna; Greil, Richard; Thieblem...espandi
info:eu-repo/semantics/article
1 Contributo su Rivista::1.1 Articolo in rivista
262
41
open
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11699/66019
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