Influenza is one of the most common respiratory viral infections worldwide. Numerous vaccines are used to prevent influenza. Their selection should be informed by the best available evidence. We aimed to estimate the comparative efficacy and safety of seasonal influenza vaccines in children, adults and the elderly.

Comparative efficacy and safety of vaccines to prevent seasonal influenza: A systematic review and network meta-analysis

Bonovas, Stefanos;
2022

Abstract

Influenza is one of the most common respiratory viral infections worldwide. Numerous vaccines are used to prevent influenza. Their selection should be informed by the best available evidence. We aimed to estimate the comparative efficacy and safety of seasonal influenza vaccines in children, adults and the elderly.
3-IIV HD, trivalent inactivated high-dose influenza vaccine
3-IIV ID, trivalent inactivated intradermal influenza vaccine
3-IIV MF59/AS03-adj, trivalent inactivated influenza vaccine adjuvanted with MF59/AS03
3-IIV vir/lip-adj, trivalent inactivated influenza vaccine adjuvanted with virosome/liposome
3-IIV, trivalent inactivated influenza vaccine
3-LAIV, trivalent live-attenuated influenza vaccine
3-RIV, trivalent recombinant influenza vaccine
4-IIV HD, quadrivalent inactivated high-dose influenza vaccine
4-IIV ID, quadrivalent inactivated intradermal influenza vaccine
4-IIV MF59/AS03-adj, quadrivalent inactivated influenza vaccine adjuvanted with MF59/AS03
4-IIV vir/lip-adj, quadrivalent inactivated influenza vaccine adjuvanted with virosome/liposome
4-IIV, quadrivalent inactivated influenza vaccine
4-LAIV, quadrivalent live-attenuated influenza vaccine
4-RIV, quadrivalent recombinant influenza vaccine
AE, adverse event
CI, confidence interval
CrI, credible interval
IIV, inactivated influenza vaccine
ILI, influenza-like illness
Influenza
LAIV, live-attenuated influenza vaccine
NMA, network meta-analysis
Network meta-analysis
RCT, randomized controlled trial
RIV, recombinant influenza vaccine
RR, risk ratio
SUCRA, surface under the cumulative ranking curve
Systematic review
Vaccines
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11699/66046
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