Effect of radiotherapy after mastectomy and axillary surgery on 10-year recurrence and 20-year breast cancer mortality: meta-analysis of individual patient data for 8135 women in 22 randomised trials

EBCTCG (Early Breast Cancer Trialists' Collaborative Group),; Mcgale, P; Taylor, C; Correa, C; Cutter, D; Duane, F; Ewertz, M; Gray, R; Mannu, G; Peto, R; Whelan, T; Wang, Y; Wang, Z; Collaborators (635)


Abe O, Darby S.; Abe, R; Enomoto, K; Kikuchi, K; Koyama, H; Masuda, H; Nomura, Y; Ohashi, Y; Sakai, K; Sugimachi, K; Toi, M; Tominaga, T; Uchino, J; Yoshida, M; Haybittle, Jl; Leonard, Cf; Calais, G; Geraud, P; Collett, V; Davies, C; Delmestri, A; Sayer, J; Harvey, Vj; Holdaway, Im; Kay, Rg; Mason, Bh; Forbes, Jf; Wilcken, N; Bartsch, R; Dubsky, P; Fesl, C; Fohler, H; Gnant, M; Greil, R; Jakesz, R; Lang, A; Luschin-Ebengreuth, G; Marth, C; Mlineritsch, B; Samonigg, H; Singer, Cf; Steger, Gg; Stöger, H; Canney, P; Yosef, Hm; Focan, C; Peek, U; Oates, Gd; Powell, J; Durand, M; Mauriac, L; Di Leo, A; Dolci, S; Larsimont, D; Nogaret, Jm; Philippson, C; Piccart, Mj; Masood, Mb; Parker, D; Price, Jj; Lindsay, Ma; Mackey, J; Martin, M; Hupperets, Ps; Bates, T; Blamey, Rw; Chetty, U; Ellis, Io; Mallon, E; Morgan, Da; Patnick, J; Pinder, S; Olivotto, I; Ragaz, J; Berry, D; Broadwater, G; Cirrincione, C; Muss, H; Norton, L; Weiss, Rb; Abu-Zahra, Ht; Portnoj, Sm; Bowden, S; Brookes, C; Dunn, J; Fernando, I; Lee, M; Poole, C; Rea, D; Spooner, D; Barrett-Lee, Pj; Mansel, Re; Monypenny, Ij; Gordon, Nh; Davis, Hl; Cuzick, J; Lehingue, Y; Romestaing, P; Dubois, Jb; Delozier, T; Griffon, B; Mace Lesech, J; Brain, E; de La Lande, B; Mouret-Fourme, E; Mustacchi, G; Petruzelka, L; Pribylova, O; Owen, Jr; Harbeck, N; Jänicke, F; Meisner, C; Schmitt, M; Thomssen, C; Meier, P; Shan, Y; Shao, Yf; Wang, X; Zhao, Db; Chen, Zm; Pan, Hc; Howell, A; Swindell, R; Burrett, Ja; Clarke, M; Collins, R; Correa, C; Cutter, D; Darby, S; Davies, C; Davies, K; Delmestri, A; Elphinstone, P; Evans, V; Gettins, L; Godwin, J; Gray, R; Gregory, C; Hermans, D; Hicks, C; James, S; Kerr, A; Liu, H; Mackinnon, E; Lay, M; Mcgale, P; Mchugh, T; Morris, P; Pan, Hc; Peto, R; Sayer, J; Taylor, C; Wang, Y; Albano, J; de Oliveira CF,; Gervásio, H; Gordilho, J; Ejlertsen, B; Jensen, Mb; Johansen, H; Mouridsen, H; Palshof, T; Gelman, Rs; Harris, Jr; Hayes, D; Henderson, C; Shapiro, Cl; Winer, E; Christiansen, P; Ejlertsen, B; Ewertz, M; Jensen, Mb; Møller, S; Mouridsen, Ht; Trampisch, Hj; Dalesio, O; de Vries EG,; Rodenhuis, S; van Tinteren, H; Comis, Rl; Davidson, Ne; Gray, R; Robert, N; Sledge, G; Solin, Lj; Sparano, Ja; Tormey, Dc; Wood, W; Cameron, D; Chetty, U; Dixon, Jm; Forrest, P; Jack, W; Kunkler, I; Rossbach, J; Klijn, Jg; Treurniet-Donker, Ad; van Putten WL,; Rotmensz, N; Veronesi, U; Viale, G; Bartelink, H; Bijker, N; Bogaerts, J; Cardoso, F; Cufer, T; Julien, Jp; Rutgers, E; van de Velde CJ,; Cunningham, Mp; Huovinen, R; Joensuu, H; Costa, A; Bonadonna, G; Gianni, L; Valagussa, P; Goldstein, Lj; Bonneterre, J; Fargeot, P; Fumoleau, P; Kerbrat, P; Luporsi, E; Namer, M; Eiermann, W; Hilfrich, J; Jonat, W; Kaufmann, M; Kreienberg, R; Schumacher, M; Bastert, G; Rauschecker, H; Sauer, R; Sauerbrei, W; Schauer, A; Schumacher, M; Blohmer, Ju; Costa, Sd; Eidtmann, H; Gerber, B; Jackisch, C; Loibl, S; von Minckwitz, G; de Schryver, A; Vakaet, L; Belfiglio, M; Nicolucci, A; Pellegrini, F; Pirozzoli, Mc; Sacco, M; Valentini, M; Mcardle, Cs; Smith, Dc; Stallard, S; Dent, Dm; Gudgeon, Ca; Hacking, A; Murray, E; Panieri, E; Werner, Id; Carrasco, E; Martin, M; Segui, Ma; Galligioni, E; Lopez, M; Erazo, A; Medina, Jy; Horiguchi, J; Takei, H; Fentiman, Is; Hayward, Jl; Rubens, Rd; Skilton, D; Scheurlen, H; Kaufmann, M; Sohn, Hc; Untch, M; Dafni, U; Markopoulos, C; Dafni, U; Fountzilas, G; Mavroudis, D; Klefstrom, P; Blomqvist, C; Saarto, T; Gallen, M; Tinterri, C; Margreiter, R; de Lafontan, B; Mihura, J; Roché, H; Asselain, B; Salmon, Rj; Vilcoq, Jr; André, F; Arriagada, R; Delaloge, S; Hill, C; Koscielny, S; Michiels, S; Rubino, C; A'Hern, R; Bliss, J; Ellis, P; Kilburn, L; Yarnold, Jr; Benraadt, J; Kooi, M; van de Velde AO,; van Dongen JA,; Vermorken, Jb; Castiglione, M; Coates, A; Colleoni, M; Collins, J; Forbes, J; Gelber, Rd; Goldhirsch, A; Lindtner, J; Price, Kn; Regan, Mm; Rudenstam, Cm; Senn, Hj; Thuerlimann, B; Bliss, Jm; Chilvers, Ce; Coombes, Rc; Hall, E; Marty, M; Buyse, M; Possinger, K; Schmid, P; Untch, M; Wallwiener, D; Foster, L; George, Wd; Stewart, Hj; Stroner, P; Borovik, R; Hayat, H; Inbar, Mj; Peretz, T; Robinson, E; Bruzzi, P; Del Mastro, L; Pronzato, P; Sertoli, Mr; Venturini, M; Camerini, T; De Palo, G; Di Mauro MG,; Formelli, F; Valagussa, P; Amadori, D; Martoni, A; Pannuti, F; Camisa, R; Cocconi, G; Colozza, A; Passalacqua, R; Aogi, K; Takashima, S; Abe, O; Ikeda, T; Inokuchi, K; Kikuchi, K; Sawa, K; Sonoo, H; Korzeniowski, S; Skolyszewski, J; Ogawa, M; Yamashita, J; Bastiaannet, E; van de Velde CJ,; van de Water, W; van Nes JG,; Christiaens, R; Neven, P; Paridaens, R; Van den Bogaert, W; Braun, S; Martin, P; Romain, S; Janauer, M; Seifert, M; Sevelda, P; Zielinski, Cc; Hakes, T; Hudis, Ca; Norton, L; Wittes, R; Giokas, G; Kondylis, D; Lissaios, B; de la Huerta, R; Sainz, Mg; Altemus, R; Camphausen, K; Cowan, K; Danforth, D; Lichter, A; Lippman, M; O'Shaughnessy, J; Pierce, Lj; Steinberg, S; Venzon, D; Zujewski, Ja; D'Amico, C; Lioce, M; Paradiso, A; Chapman, Ja; Gelmon, K; Goss, Pe; Levine, Mn; Meyer, R; Parulekar, W; Pater, Jl; Pritchard, Ki; Shepherd, Le; D, Tu; Whelan, T; Nomura, Y; Ohno, S; Anderson, S; Bass, G; Brown, A; Bryant, J; Costantino, J; Dignam, J; Fisher, B; Geyer, C; Mamounas, Ep; Paik, S; Redmond, C; Swain, S; Wickerham, L; Wolmark, N; Baum, M; Jackson, Im; Palmer, Mk; Perez, E; Ingle, Jn; Suman, Vj; Bengtsson, No; Emdin, S; Jonsson, H; Del Mastro, L; Venturini, M; Lythgoe, Jp; Swindell, R; Kissin, M; Erikstein, B; Hannisdal, E; Jacobsen, Ab; Varhaug, Je; Erikstein, B; Gundersen, S; Hauer-Jensen, M; Høst, H; Jacobsen, Ab; Nissen-Meyer, R; Reinertsen, K; Blamey, Rw; Mitchell, Ak; Morgan, Da; Robertson, Jf; Ueo, H; Di Palma, M; Mathé, G; Misset, Jl; Levine, M; Pritchard, Ki; Whelan, T; Morimoto, K; Sawa, K; Takatsuka, Y; Crossley, E; Harris, A; Talbot, D; Taylor, M; Cocconi, G; di Blasio, B; Ivanov, V; Paltuev, R; Semiglazov, V; Brockschmidt, J; Cooper, Mr; Falkson, Ci; A'Hern, R; Dowsett, M; Makris, A; Parton, M; Pennert, K; Powles, Tj; Smith, Ie; Yarnold, Jr; Gazet, Jc; Browne, L; Graham, P; Corcoran, N; Businico, A; Deshpande, N; di Martino, L; Douglas, P; Hacking, A; Høst, H; Lindtner, A; Notter, G; Bryant, Aj; Ewing, Gh; Firth, La; Krushen-Kosloski, Jl; Nissen-Meyer, R; Anderson, H; Killander, F; Malmström, P; Rydén, L; Arnesson, Lg; Carstensen, J; Dufmats, M; Fohlin, H; Nordenskjöld, B; Söderberg, M; Carpenter, Jt; Murray, N; Royle, Gt; Simmonds, Pd; Albain, K; Barlow, W; Crowley, J; Hayes, D; Gralow, J; Hortobagyi, G; Livingston, R; Martino, S; Osborne, Ck; Ravdin, Pm; Adolfsson, J; Bergh, J; Bondesson, T; Celebioglu, F; Dahlberg, K; Fornander, T; Fredriksson, I; Frisell, J; Göransson, E; Iiristo, M; Johansson, U; Lenner, E; Löfgren, L; Nikolaidis, P; Perbeck, L; Rotstein, S; Sandelin, K; Skoog, L; Svane, G; af Trampe, E; Wadström, C; Janni, W; Castiglione, M; Goldhirsch, A; Maibach, R; Senn, Hj; Thürlimann, B; Hakama, M; Holli, K; Isola, J; Rouhento, K; Saaristo, R; Brenner, H; Hercbergs, A; Yoshimoto, M; Paterson, Ah; Pritchard, Ki; Fyles, A; Meakin, Jw; Panzarella, T; Pritchard, Ki; Bahi, J; Reid, M; Spittle, M; Bishop, H; Bundred, Nj; Cuzick, J; Ellis, Io; Fentiman, Is; Forbes, Jf; Forsyth, S; George, Wd; Pinder, Se; Sestak, I; Deutsch, Gp; Gray, R; Kwong, Dl; Pai, Vr; Peto, R; Senanayake, F; Martin, Al; Roché, H; Boccardo, F; Rubagotti, A; Baum, M; Forsyth, S; Hackshaw, A; Houghton, J; Ledermann, J; Monson, K; Tobias, Js; Carlomagno, C; De Laurentiis, M; De Placido, S; Williams, L; Hayes, D; Pierce, Lj; Broglio, K; Buzdar, Au; Hsu, L; Love, Rr; Ahlgren, J; Garmo, H; Holmberg, L; Liljegren, G; Lindman, H; Wärnberg, F; Asmar, L; Jones, Se; Gluz, O; Harbeck, N; Liedtke, C; Nitz, U; Litton, A; Wallgren, A; Karlsson, P; Linderholm, Bk; Chlebowski, Rt; Caffier, H

doi:10.1016/S0140-6736(14)60488-8

Effect of radiotherapy after mastectomy and axillary surgery on 10-year recurrence and 20-year breast cancer mortality: meta-analysis of individual patient data for 8135 women in 22 randomised trials

McGale P;Taylor C;Correa C;Cutter D;Duane F;Ewertz M;Gray R;Mannu G;Peto R;Whelan T;Wang Y;Wang Z;Abe R;Enomoto K;Kikuchi K;Koyama H;Masuda H;Nomura Y;Ohashi Y;Sakai K;Sugimachi K;Toi M;Tominaga T;Uchino J;Yoshida M;Haybittle JL;Leonard CF;Calais G;Geraud P;Collett V;Davies C;Delmestri A;Sayer J;Harvey VJ;Holdaway IM;Kay RG;Mason BH;Forbes JF;Wilcken N;Bartsch R;Dubsky P;Fesl C;Fohler H;Gnant M;Greil R;Jakesz R;Lang A;Luschin-Ebengreuth G;Marth C;Mlineritsch B;Samonigg H;Singer CF;Steger GG;Stöger H;Canney P;Yosef HM;Focan C;Peek U;Oates GD;Powell J;Durand M;Mauriac L;Di Leo A;Dolci S;Larsimont D;Nogaret JM;Philippson C;Piccart MJ;Masood MB;Parker D;Price JJ;Lindsay MA;Mackey J;Martin M;Hupperets PS;Bates T;Blamey RW;Chetty U;Ellis IO;Mallon E;Morgan DA;Patnick J;Pinder S;Olivotto I;Ragaz J;Berry D;Broadwater G;Cirrincione C;Muss H;Norton L;Weiss RB;Abu-Zahra HT;Portnoj SM;Bowden S;Brookes C;Dunn J;Fernando I;Lee M;Poole C;Rea D;Spooner D;Barrett-Lee PJ;Mansel RE;Monypenny IJ;Gordon NH;Davis HL;Cuzick J;Lehingue Y;Romestaing P;Dubois JB;Delozier T;Griffon B;Mace Lesech J;Brain E;de La Lande B;Mouret-Fourme E;Mustacchi G;Petruzelka L;Pribylova O;Owen JR;Harbeck N;Jänicke F;Meisner C;Schmitt M;Thomssen C;Meier P;Shan Y;Shao YF;Wang X;Zhao DB;Chen ZM;Pan HC;Howell A;Swindell R;Burrett JA;Clarke M;Collins R;Correa C;Cutter D;Darby S;Davies C;Davies K;Delmestri A;Elphinstone P;Evans V;Gettins L;Godwin J;Gray R;Gregory C;Hermans D;Hicks C;James S;Kerr A;Liu H;MacKinnon E;Lay M;McGale P;McHugh T;Morris P;Pan HC;Peto R;Sayer J;Taylor C;Wang Y;Albano J;de Oliveira CF;Gervásio H;Gordilho J;Ejlertsen B;Jensen MB;Johansen H;Mouridsen H;Palshof T;Gelman RS;Harris JR;Hayes D;Henderson C;Shapiro CL;Winer E;Christiansen P;Ejlertsen B;Ewertz M;Jensen MB;Møller S;Mouridsen HT;Trampisch HJ;Dalesio O;de Vries EG;Rodenhuis S;van Tinteren H;Comis RL;Davidson NE;Gray R;Robert N;Sledge G;Solin LJ;Sparano JA;Tormey DC;Wood W;Cameron D;Chetty U;Dixon JM;Forrest P;Jack W;Kunkler I;Rossbach J;Klijn JG;Treurniet-Donker AD;van Putten WL;Rotmensz N;Veronesi U;Viale G;Bartelink H;Bijker N;Bogaerts J;Cardoso F;Cufer T;Julien JP;Rutgers E;van de Velde CJ;Cunningham MP;Huovinen R;Joensuu H;Costa A;Bonadonna G;Gianni L;Valagussa P;Goldstein LJ;Bonneterre J;Fargeot P;Fumoleau P;Kerbrat P;Luporsi E;Namer M;Eiermann W;Hilfrich J;Jonat W;Kaufmann M;Kreienberg R;Schumacher M;Bastert G;Rauschecker H;Sauer R;Sauerbrei W;Schauer A;Schumacher M;Blohmer JU;Costa SD;Eidtmann H;Gerber B;Jackisch C;Loibl S;von Minckwitz G;de Schryver A;Vakaet L;Belfiglio M;Nicolucci A;Pellegrini F;Pirozzoli MC;Sacco M;Valentini M;McArdle CS;Smith DC;Stallard S;Dent DM;Gudgeon CA;Hacking A;Murray E;Panieri E;Werner ID;Carrasco E;Martin M;Segui MA;Galligioni E;Lopez M;Erazo A;Medina JY;Horiguchi J;Takei H;Fentiman IS;Hayward JL;Rubens RD;Skilton D;Scheurlen H;Kaufmann M;Sohn HC;Untch M;Dafni U;Markopoulos C;Dafni U;Fountzilas G;Mavroudis D;Klefstrom P;Blomqvist C;Saarto T;Gallen M;Tinterri C;Margreiter R;de Lafontan B;Mihura J;Roché H;Asselain B;Salmon RJ;Vilcoq JR;André F;Arriagada R;Delaloge S;Hill C;Koscielny S;Michiels S;Rubino C;A'Hern R;Bliss J;Ellis P;Kilburn L;Yarnold JR;Benraadt J;Kooi M;van de Velde AO;van Dongen JA;Vermorken JB;Castiglione M;Coates A;Colleoni M;Collins J;Forbes J;Gelber RD;Goldhirsch A;Lindtner J;Price KN;Regan MM;Rudenstam CM;Senn HJ;Thuerlimann B;Bliss JM;Chilvers CE;Coombes RC;Hall E;Marty M;Buyse M;Possinger K;Schmid P;Untch M;Wallwiener D;Foster L;George WD;Stewart HJ;Stroner P;Borovik R;Hayat H;Inbar MJ;Peretz T;Robinson E;Bruzzi P;Del Mastro L;Pronzato P;Sertoli MR;Venturini M;Camerini T;De Palo G;Di Mauro MG;Formelli F;Valagussa P;Amadori D;Martoni A;Pannuti F;Camisa R;Cocconi G;Colozza A;Passalacqua R;Aogi K;Takashima S;Abe O;Ikeda T;Inokuchi K;Kikuchi K;Sawa K;Sonoo H;Korzeniowski S;Skolyszewski J;Ogawa M;Yamashita J;Bastiaannet E;van de Velde CJ;van de Water W;van Nes JG;Christiaens R;Neven P;Paridaens R;Van den Bogaert W;Braun S;Martin P;Romain S;Janauer M;Seifert M;Sevelda P;Zielinski CC;Hakes T;Hudis CA;Norton L;Wittes R;Giokas G;Kondylis D;Lissaios B;de la Huerta R;Sainz MG;Altemus R;Camphausen K;Cowan K;Danforth D;Lichter A;Lippman M;O'Shaughnessy J;Pierce LJ;Steinberg S;Venzon D;Zujewski JA;D'Amico C;Lioce M;Paradiso A;Chapman JA;Gelmon K;Goss PE;Levine MN;Meyer R;Parulekar W;Pater JL;Pritchard KI;Shepherd LE;Tu D;Whelan T;Nomura Y;Ohno S;Anderson S;Bass G;Brown A;Bryant J;Costantino J;Dignam J;Fisher B;Geyer C;Mamounas EP;Paik S;Redmond C;Swain S;Wickerham L;Wolmark N;Baum M;Jackson IM;Palmer MK;Perez E;Ingle JN;Suman VJ;Bengtsson NO;Emdin S;Jonsson H;Del Mastro L;Venturini M;Lythgoe JP;Swindell R;Kissin M;Erikstein B;Hannisdal E;Jacobsen AB;Varhaug JE;Erikstein B;Gundersen S;Hauer-Jensen M;Høst H;Jacobsen AB;Nissen-Meyer R;Reinertsen K;Blamey RW;Mitchell AK;Morgan DA;Robertson JF;Ueo H;Di Palma M;Mathé G;Misset JL;Levine M;Pritchard KI;Whelan T;Morimoto K;Sawa K;Takatsuka Y;Crossley E;Harris A;Talbot D;Taylor M;Cocconi G;di Blasio B;Ivanov V;Paltuev R;Semiglazov V;Brockschmidt J;Cooper MR;Falkson CI;A'Hern R;Dowsett M;Makris A;Parton M;Pennert K;Powles TJ;Smith IE;Yarnold JR;Gazet JC;Browne L;Graham P;Corcoran N;Businico A;Deshpande N;di Martino L;Douglas P;Hacking A;Høst H;Lindtner A;Notter G;Bryant AJ;Ewing GH;Firth LA;Krushen-Kosloski JL;Nissen-Meyer R;Anderson H;Killander F;Malmström P;Rydén L;Arnesson LG;Carstensen J;Dufmats M;Fohlin H;Nordenskjöld B;Söderberg M;Carpenter JT;Murray N;Royle GT;Simmonds PD;Albain K;Barlow W;Crowley J;Hayes D;Gralow J;Hortobagyi G;Livingston R;Martino S;Osborne CK;Ravdin PM;Adolfsson J;Bergh J;Bondesson T;Celebioglu F;Dahlberg K;Fornander T;Fredriksson I;Frisell J;Göransson E;Iiristo M;Johansson U;Lenner E;Löfgren L;Nikolaidis P;Perbeck L;Rotstein S;Sandelin K;Skoog L;Svane G;af Trampe E;Wadström C;Janni W;Castiglione M;Goldhirsch A;Maibach R;Senn HJ;Thürlimann B;Hakama M;Holli K;Isola J;Rouhento K;Saaristo R;Brenner H;Hercbergs A;Yoshimoto M;Paterson AH;Pritchard KI;Fyles A;Meakin JW;Panzarella T;Pritchard KI;Bahi J;Reid M;Spittle M;Bishop H;Bundred NJ;Cuzick J;Ellis IO;Fentiman IS;Forbes JF;Forsyth S;George WD;Pinder SE;Sestak I;Deutsch GP;Gray R;Kwong DL;Pai VR;Peto R;Senanayake F;Martin AL;Roché H;Boccardo F;Rubagotti A;Baum M;Forsyth S;Hackshaw A;Houghton J;Ledermann J;Monson K;Tobias JS;Carlomagno C;De Laurentiis M;De Placido S;Williams L;Hayes D;Pierce LJ;Broglio K;Buzdar AU;Hsu L;Love RR;Ahlgren J;Garmo H;Holmberg L;Liljegren G;Lindman H;Wärnberg F;Asmar L;Jones SE;Gluz O;Harbeck N;Liedtke C;Nitz U;Litton A;Wallgren A;Karlsson P;Linderholm BK;Chlebowski RT;Caffier H

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Effect of radiotherapy after mastectomy and axillary surgery on 10-year recurrence and 20-year breast cancer mortality: meta-analysis of individual patient data for 8135 women in 22 randomised trials

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