Aromatase inhibitors versus tamoxifen in early breast cancer: patient-level meta-analysis of the randomised trials

Early Breast Cancer Trialists' Collaborative Group (EBCTCG);Dowsett M;Forbes JF;Bradley R;Ingle J;Aihara T;Bliss J;Boccardo F;Coates A;Coombes RC;Cuzick J;Dubsky P;Gnant M;Kaufmann M;Kilburn L;Perrone F;Rea D;Thürlimann B;van de Velde C;Pan H;Peto R;Davies C;Gray R. Collaborators (764) Bradley R;Burrett J;Clarke M;Davies C;Duane F;Evans V;Gettins L;Godwin J;Gray R;Liu H;McGale P;MacKinnon E;McHugh T;James S;Morris P;Pan H;Peto R;Read S;Taylor C;Wang Y;Wang Z;Bradley R;Davies C;Gray R;Pan H;Peto R;Dowsett M;Bradley R;Forbes JF;Ingle J;Gray R;Coates A;Cuzick J;Gnant M;Peto R;Bergh J;Pritchard K;Albain K;Anderson S;Arriagada R;Barlow W;Bergsten-Nordström E;Bliss J;Boccardo F;Bradley R;Buyse M;Cameron D;Clarke M;Coates A;Coleman R;Correa C;Costantino J;Cuzick J;Davidson N;Davies C;Di Leo A;Dowsett M;Ewertz M;Forbes J;Gelber R;Geyer C;Gianni L;Gnant M;Goldhirsch A;Gray R;Hayes D;Hill C;Ingle J;Janni W;MacKinnon E;Martín M;McGale P;Norton L;Ohashi Y;Paik S;Pan H;Perez E;Peto R;Piccart M;Pierce L;Raina V;Ravdin P;Robertson J;Rutgers E;Sparano J;Swain S;Taylor C;Viale G;von Minckwitz G;Wang X;Whelan T;Wilcken N;Winer E;Wolmark N;Wood W;Abe O;Abe R;Enomoto K;Kikuchi K;Koyama H;Masuda H;Nomura Y;Ohashi Y;Sakai K;Sugimachi K;Toi M;Tominaga T;Uchino J;Yoshida M;Haybittle JL;Leonard CF;Calais G;Garaud P;Collett V;Davies C;Delmestri A;Sayer J;Harvey VJ;Holdaway IM;Kay RG;Mason BH;Forbes JF;Wilcken N;Bartsch R;Dubsky P;Fesl C;Fohler H;Gnant M;Greil R;Jakesz R;Lang A;Luschin-Ebengreuth G;Marth C;Mlineritsch B;Samonigg H;Singer CF;Steger GG;Stöger H;Canney P;Yosef HM;Focan C;Peek U;Oates GD;Powell J;Durand M;Mauriac L;Di Leo A;Dolci S;Larsimont D;Nogaret JM;Philippson C;Piccart MJ;Masood MB;Parker D;Price JJ;Lindsay MA;Mackey J;Martin M;Hupperets PS;Bates T;Blamey RW;Chetty U;Ellis IO;Mallon E;Morgan DA;Patnick J;Pinder S;Olivotto I;Ragaz J;Berry D;Broadwater G;Cirrincione C;Muss H;Norton L;Weiss RB;Abu-Zahra HT;Portnoj SM;Bowden S;Brookes C;Dunn J;Fernando I;Lee M;Poole C;Rea D;Spooner D;Barrett-Lee PJ;Mansel RE;Monypenny IJ;Gordon NH;Davis HL;Cuzick J;Sestak I;Lehingue Y;Romestaing P;Dubois JB;Delozier T;Griffon B;Mace Lesec'h J;Brain E;de La Lande B;Mouret-Fourme E;Mustacchi G;Petruzelka L;Pribylova O;Owen JR;Harbeck N;Jänicke F;Meisner C;Schmitt M;Thomssen C;Meier P;Shan Y;Shao YF;Wang X;Zhao DB;Chen ZM;Pan HC;Howell A;Swindell R;Bradley R;Burrett JA;Clarke M;Cutter D;Davies C;Duane F;Evans V;Gettins L;Godwin J;Gray R;James S;Kerr A;Liu H;MacKinnon E;Mannu G;McGale P;McHugh T;Morris P;Pan HC;Peto R;Read S;Taylor C;Wang Y;Wang Z;Albano J;de Oliveira CF;Gervásio H;Gordilho J;Ejlertsen B;Jensen MB;Johansen H;Mouridsen H;Palshof T;Gelman RS;Harris JR;Hayes D;Henderson C;Shapiro CL;Winer E;Christiansen P;Ejlertsen B;Ewertz M;Jensen MB;Møller S;Mouridsen HT;Trampisch HJ;Dalesio O;de Vries EG;Rodenhuis S;van Tinteren H;Comis RL;Davidson NE;Gray R;Robert N;Sledge G;Solin LJ;Sparano JA;Tormey DC;Wood W;Cameron D;Chetty U;Dixon JM;Forrest P;Jack W;Kunkler I;Rossbach J;Klijn JG;Treurniet-Donker AD;van Putten WL;Rotmensz N;Veronesi U;Viale G;Bartelink H;Bijker N;Bogaerts J;Cardoso F;Cufer T;Julien JP;Rutgers E;van de Velde CJ;Cunningham MP;Huovinen R;Joensuu H;Costa A;Bonadonna G;Gianni L;Valagussa P;Goldstein LJ;Bonneterre J;Fargeot P;Fumoleau P;Kerbrat P;Luporsi E;Namer M;Eiermann W;Hilfrich J;Jonat W;Kaufmann M;Kreienberg R;Schumacher M;Bastert G;Rauschecker H;Sauer R;Sauerbrei W;Schauer A;Schumacher M;Blohmer JU;Costa SD;Eidtmann H;Gerber B;Jackisch C;Loibl S;von Minckwitz G;de Schryver A;Vakaet L;Belfiglio M;Nicolucci A;Pellegrini F;Pirozzoli MC;Sacco M;Valentini M;McArdle CS;Smith DC;Stallard S;Dent DM;Gudgeon CA;Hacking A;Murray E;Panieri E;Werner ID;Carrasco E;Martin M;Segui MA;Galligioni E;Leone B;Vallejo CT;Zwenger A;Lopez M;Erazo A;Medina JY;Horiguchi J;Takei H;Fentiman IS;Hayward JL;Rubens RD;Skilton D;Scheurlen H;Kaufmann M;Sohn HC;Untch M;Dafni U;Markopoulos C;Dafni U;Fountzilas G;Mavroudis D;Klefstrom P;Blomqvist C;Saarto T;Gallen M;Tinterri C;Margreiter R;de Lafontan B;Mihura J;Roché H;Asselain B;Salmon RJ;Vilcoq JR;André F;Arriagada R;Delaloge S;Hill C;Koscielny S;Michiels S;Rubino C;A'Hern R;Bliss J;Ellis P;Kilburn L;Yarnold JR;Benraadt J;Kooi M;van de Velde AO;van Dongen JA;Vermorken JB;Castiglione M;Coates A;Colleoni M;Collins J;Forbes J;Gelber RD;Goldhirsch A;Lindtner J;Price KN;Regan MM;Rudenstam CM;Senn HJ;Thuerlimann B;Bliss JM;Chilvers CE;Coombes RC;Hall E;Marty M;Buyse M;Possinger K;Schmid P;Untch M;Wallwiener D;Foster L;George WD;Stewart HJ;Stroner P;Borovik R;Hayat H;Inbar MJ;Peretz T;Robinson E;Bruzzi P;Del Mastro L;Pronzato P;Sertoli MR;Venturini M;Camerini T;De Palo G;Di Mauro MG;Formelli F;Valagussa P;Perrone F;Amadori D;Martoni A;Pannuti F;Camisa R;Cocconi G;Colozza A;Passalacqua R;Aogi K;Takashima S;Abe O;Ikeda T;Inokuchi K;Kikuchi K;Sawa K;Sonoo H;Sadoon M;Tulusan AH;Kohno N;Miyashita M;Takao S;Ahn JH;Jung KH;Korzeniowski S;Skolyszewski J;Ogawa M;Yamashita J;Bastiaannet E;van de Velde CJ;van de Water W;van Nes JG;Christiaens R;Neven P;Paridaens R;Van den Bogaert W;Braun S;Martin P;Romain S;Janauer M;Seifert M;Sevelda P;Zielinski CC;Hakes T;Hudis CA;Norton L;Wittes R;Giokas G;Kondylis D;Lissaios B;de la Huerta R;Sainz MG;Ro J;Altemus R;Camphausen K;Cowan K;Danforth D;Lichter A;Lippman M;O'Shaughnessy J;Pierce LJ;Steinberg S;Venzon D;Zujewski JA;D'Amico C;Lioce M;Paradiso A;Chapman JA;Gelmon K;Goss PE;Levine MN;Meyer R;Parulekar W;Pater JL;Pritchard KI;Shepherd LE;Tu D;Whelan T;Nomura Y;Ohno S;Anderson S;Bass G;Brown A;Bryant J;Costantino J;Dignam J;Fisher B;Geyer C;Mamounas EP;Paik S;Redmond C;Swain S;Wickerham L;Wolmark N;Aihara T;Hozumi Y;Nomura Y;Baum M;Jackson IM;Palmer MK;Perez E;Ingle JN;Suman VJ;Bengtsson NO;Emdin S;Jonsson H;Del Mastro L;Venturini M;Lythgoe JP;Swindell R;Kissin M;Erikstein B;Hannisdal E;Jacobsen AB;Varhaug JE;Erikstein B;Gundersen S;Hauer-Jensen M;Høst H;Jacobsen Nissen-Meyer;Blamey RW;Mitchell AK;Morgan DA;Robertson JF;Ueo H;Di Palma M;Mathé G;Misset JL;Levine M;Pritchard KI;Whelan T;Morimoto K;Sawa K;Takatsuka Y;Crossley E;Harris A;Talbot D;Taylor M;Cocconi G;di Blasio B;Ivanov V;Paltuev R;Semiglazov V;Brockschmidt J;Cooper MR;Falkson CI;Hadji P;A'Hern R;Dowsett M;Makris A;Parton M;Pennert K;Powles TJ;Smith IE;Yarnold JR;Gazet JC;Browne L;Graham P;Corcoran N;Clack G;Van Poznak C;Businico A;Deshpande N;di Martino L;Douglas P;Hacking A;Høst H;Lindtner A;Notter G;Bryant AJ;Ewing GH;Firth LA;Krushen-Kosloski JL;Nissen-Meyer R;Anderson H;Killander F;Malmström P;Rydén L;Arnesson LG;Carstensen J;Dufmats M;Fohlin H;Nordenskjöld B;Söderberg M;Carpenter JT;Murray N;Royle GT;Simmonds PD;Albain K;Barlow W;Crowley J;Hayes D;Gralow J;Hortobagyi G;Livingston R;Martino S;Osborne CK;Ravdin PM;Adolfsson J;Bergh J;Bondesson T;Celebioglu F;Dahlberg K;Fornander T;Fredriksson I;Frisell J;Göransson E;Iiristo M;Johansson U;Lenner E;Löfgren L;Nikolaidis P;Perbeck L;Rotstein S;Sandelin K;Skoog L;Svane G;af Trampe E;Wadström C;Janni W;Castiglione M;Goldhirsch A;Maibach R;Senn HJ;Thürlimann B;Bastiaannet E;Hadji P;Hozumi Y;Rea D;van de Velde CJ;Hakama M;Holli K;Isola J;Rouhento K;Saaristo R;Safra T;Brenner H;Hercbergs A;Yoshimoto M;Paterson AH;Pritchard KI;Fyles A;Meakin JW;Panzarella T;Pritchard KI;Bahi J;Reid M;Spittle M;Bishop H;Bundred NJ;Cuzick J;Ellis IO;Fentiman IS;Forbes JF;Forsyth S;George WD;Pinder SE;Sestak I;Deutsch GP;Gray R;Kwong DL;Pai VR;Peto R;Senanayake F;Martin AL;Roché H;Boccardo F;Rubagotti A;Baum M;Forsyth S;Hackshaw A;Houghton J;Ledermann J;Monson K;Tobias JS;Carlomagno C;De Laurentiis M;De Placido S;Williams L;Bell R;Cameron D;Coleman RE;Dodwell D;Hinsley S;Marshall HC;Hayes D;Pierce LJ;Solomayer E;Fehm T;Coleman RE;Horsman JM;Lester J;Winter MC;Broglio K;Buzdar AU;Hsu L;Love RR;Ahlgren J;Garmo H;Holmberg L;Liljegren G;Lindman H;Wärnberg F;Asmar L;Jones SE;Aft R;Gluz O;Harbeck N;Liedtke C;Nitz U;Litton A;Wallgren A;Karlsson P;Linderholm BK;Chlebowski RT;Caffier H;Brufsky AM;Coleman RE;Llombart HA

2015-01-01