Type II collagen is a DR4/DR1 restricted target of self-reactive T cells that sustain rheumatoid arthritis. The aim of the present study was to analyze the T-cell receptor repertoire at the onset of and at different phases in rheumatoid arthritis.

Collagen-specific T-cell repertoire in blood and synovial fluid varies with disease activity in early rheumatoid arthritis

De Santis, Maria;
2008-01-01

Abstract

Type II collagen is a DR4/DR1 restricted target of self-reactive T cells that sustain rheumatoid arthritis. The aim of the present study was to analyze the T-cell receptor repertoire at the onset of and at different phases in rheumatoid arthritis.
Adult
Aged
Amino Acid Motifs
Amino Acid Sequence
Arthritis, Rheumatoid
Cell Proliferation
Cohort Studies
Collagen Type II
Epitopes, T-Lymphocyte
Female
Gene Rearrangement, alpha-Chain T-Cell Antigen Receptor
Humans
Middle Aged
Molecular Sequence Data
Synovial Fluid
T-Lymphocytes
Time Factors
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11699/68423
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