To investigate the role of the HS1,2 enhancer polymorphisms as a new candidate marker for rheumatoid arthritis (RA) and to define the possible association with autoantibody positivity and clinical outcome.

Allele *2 of the HS1,2A enhancer of the Ig regulatory region associates with rheumatoid arthritis

De Santis, M;
2009

Abstract

To investigate the role of the HS1,2 enhancer polymorphisms as a new candidate marker for rheumatoid arthritis (RA) and to define the possible association with autoantibody positivity and clinical outcome.
Adult
Aged
Antirheumatic Agents
Arthritis, Rheumatoid
Autoantibodies
Cohort Studies
Enhancer Elements, Genetic
Female
Genetic Markers
Genetic Predisposition to Disease
Genotype
Humans
Immunoglobulin Heavy Chains
Male
Middle Aged
Phenotype
Regulatory Sequences, Nucleic Acid
Rheumatoid Factor
Severity of Illness Index
Treatment Outcome
Alleles
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11699/68424
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