Antineutrophil cytoplasmic antibodies (ANCA) are primarily involved in the pathogenesis of ANCA-associated vasculitides (AAV). However, ANCA may also be present in healthy subjects and in patients with autoimmune disorders different from AAV. We hypothesized that serum ANCA are associated with a worse prognosis in disorders other than AAV.

Serum ANCA and Overall Mortality: A 10-Year Retrospective Cohort Study on 1,024 Italian Subjects

De Santis, Maria;Furlan, Raffaello;Selmi, Carlo
2021

Abstract

Antineutrophil cytoplasmic antibodies (ANCA) are primarily involved in the pathogenesis of ANCA-associated vasculitides (AAV). However, ANCA may also be present in healthy subjects and in patients with autoimmune disorders different from AAV. We hypothesized that serum ANCA are associated with a worse prognosis in disorders other than AAV.
ANCA
cohort
retrospective
rheumatoid arthritis
vasculitis
Antibodies, Antineutrophil Cytoplasmic
Autoimmune Diseases
Humans
Italy
Kaplan-Meier Estimate
Prognosis
Proportional Hazards Models
Public Health Surveillance
Retrospective Studies
Autoimmunity
Biomarkers
Mortality
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11699/68467
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