Autoantibodies in patients with polymyositis/dermatomyositis (PM/DM) are associated with unique subsets, clinical course and outcome. Anti-MJ antibodies, which recognize the nuclear protein NXP-2/MORC3, are reported in ~25% of juvenile DM. Prevalence and clinical significance of anti-MJ antibodies in adult Italian PM/DM patients were studied.

Anti-MJ/NXP-2 autoantibody specificity in a cohort of adult Italian patients with polymyositis/dermatomyositis

Ceribelli, Angela;
2012

Abstract

Autoantibodies in patients with polymyositis/dermatomyositis (PM/DM) are associated with unique subsets, clinical course and outcome. Anti-MJ antibodies, which recognize the nuclear protein NXP-2/MORC3, are reported in ~25% of juvenile DM. Prevalence and clinical significance of anti-MJ antibodies in adult Italian PM/DM patients were studied.
Adenosine Triphosphatases
Adult
Aged
Autoantibodies
Biomarkers
Cohort Studies
DNA-Binding Proteins
Dermatomyositis
Female
Humans
Italy
K562 Cells
Male
Middle Aged
Antibody Specificity
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11699/68514
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