The present study was aimed at investigating L-asparaginase (L-ASE) activity (in plasma) and L-asparagine (L-ASN) depletion (in plasma and CSF) in children with newly diagnosed acute lymphoblastic leukemia (ALL) exposed for the first time to different L-ASE products.

L-asparagine depletion and L-asparaginase activity in children with acute lymphoblastic leukemia receiving i.m. or i.v. Erwinia C. or E. coli L-asparaginase as first exposure

D'Incalci, M
2000-01-01

Abstract

The present study was aimed at investigating L-asparaginase (L-ASE) activity (in plasma) and L-asparagine (L-ASN) depletion (in plasma and CSF) in children with newly diagnosed acute lymphoblastic leukemia (ALL) exposed for the first time to different L-ASE products.
Antineoplastic Agents
Asparaginase
Asparagine
Child
Child, Preschool
Dose-Response Relationship, Drug
Drug Administration Schedule
Escherichia coli
Female
Follow-Up Studies
Humans
Injections, Intramuscular
Injections, Intravenous
Male
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Treatment Outcome
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11699/68602
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