Klinefelter syndrome (KS) frequently causes skeletal fragility characterized by profound alterations in bone microstructure with increased risk of fractures. Increased body fat mass associated with decreased body lean mass are frequent features of KS with possible detrimental effects on skeletal health. In this cross-sectional study, we evaluated the associations between body composition parameters, vertebral fractures (VFs) and trabecular bone score (TBS) in adult subjects with KS.

Body composition, trabecular bone score and vertebral fractures in subjects with Klinefelter syndrome

Vena, W;Lania, A G;Mazziotti, G;
2023-01-01

Abstract

Klinefelter syndrome (KS) frequently causes skeletal fragility characterized by profound alterations in bone microstructure with increased risk of fractures. Increased body fat mass associated with decreased body lean mass are frequent features of KS with possible detrimental effects on skeletal health. In this cross-sectional study, we evaluated the associations between body composition parameters, vertebral fractures (VFs) and trabecular bone score (TBS) in adult subjects with KS.
2023
Body composition
Bone health
Hypogonadism
Klinefelter syndrome
Testosterone
Trabecular bone score
Vertebral fractures
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11699/68823
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