After the intravenous administration of a radiolabeled somatostatin analogue (octreotide), normal thyroid and neoplastic and nonneoplastic thyroid lesions can be visualized. The authors present the cases of two patients who underwent somatostatin receptor scintigraphy (SSRS) using in- 111 pentetreotide: one for the study of suspected paraneoplastic ACTH hypersecretion, and the other for a restaging of breast carcinoma with neuroendocrine features. In both patients, SSRS revealed increased uptake in the thyroid, corresponding to 'cold' nodules on Tc-99m pertechnetate imaging. Cytologic and histologic examinations showed the typical features of thyroid goiters without lymphocytic infiltration.

Uptake of In-111 pentetreotide by normally functioning nodular goiters

S. UCCELLA;
1997-01-01

Abstract

After the intravenous administration of a radiolabeled somatostatin analogue (octreotide), normal thyroid and neoplastic and nonneoplastic thyroid lesions can be visualized. The authors present the cases of two patients who underwent somatostatin receptor scintigraphy (SSRS) using in- 111 pentetreotide: one for the study of suspected paraneoplastic ACTH hypersecretion, and the other for a restaging of breast carcinoma with neuroendocrine features. In both patients, SSRS revealed increased uptake in the thyroid, corresponding to 'cold' nodules on Tc-99m pertechnetate imaging. Cytologic and histologic examinations showed the typical features of thyroid goiters without lymphocytic infiltration.
1997
Octreotide
Somatostatin Receptor Scintigraphy
Thyroid Diseases
Adenoma
Adrenocorticotropic Hormone
Biopsy
Needle
Breast Neoplasms
Carcinoma
Female
Goiter
Nodular
Humans
Injections
Intravenous
Middle Aged
Neoplasm Staging
Neuroendocrine Tumors
Paraneoplastic Syndromes
Pituitary Neoplasms
Radionuclide Imaging
Receptors
Somatostatin
Sodium Pertechnetate Tc 99m
Somatostatin
Thyroid Gland
Thyroid Nodule
Indium Radioisotopes
Radiopharmaceuticals
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11699/69281
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