Recently, the US Food and Drug Administration called for cautious use of anesthetic drugs during pregnancy. In 0.2-2% of pregnancies, nonobstetric surgery is being performed. The consequences of anesthesia during pregnancy on fetal development remain unclear, and preclinical studies in relevant animal models may help to elucidate them.

Maternal surgery during pregnancy has a transient adverse effect on the developing fetal rabbit brain

Inversetti, Annalisa;
2019

Abstract

Recently, the US Food and Drug Administration called for cautious use of anesthetic drugs during pregnancy. In 0.2-2% of pregnancies, nonobstetric surgery is being performed. The consequences of anesthesia during pregnancy on fetal development remain unclear, and preclinical studies in relevant animal models may help to elucidate them.
brain
cognition
development
fetus
general anesthesia
long term
maternal surgery
motor
neurobehavior
pregnancy
rabbit
Anesthesia, General
Anesthetics, Inhalation
Anesthetics, Intravenous
Animals
Blood Gas Analysis
Brain
Cell Count
Female
Laparotomy
Models, Animal
Neurons
Pregnancy
Prenatal Exposure Delayed Effects
Propofol
Rabbits
Random Allocation
Sevoflurane
Synaptophysin
Fetal Development
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11699/69846
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