Currently, preoperative staging of esophageal adenocarcinoma (EAC) has modest reliability and accuracy for pT and pN stages prediction, which heavily affects overall survival. The interplay among immune checkpoints, oncogenes, and intratumoral and peritumoral immune infiltrating cells could be used to predict loco-regional metastatic disease in early EAC.

Tumor immune microenvironment in therapy-naive esophageal adenocarcinoma could predict the nodal status

Castoro, Carlo;
2022

Abstract

Currently, preoperative staging of esophageal adenocarcinoma (EAC) has modest reliability and accuracy for pT and pN stages prediction, which heavily affects overall survival. The interplay among immune checkpoints, oncogenes, and intratumoral and peritumoral immune infiltrating cells could be used to predict loco-regional metastatic disease in early EAC.
biomarkers
esophageal adenocarcinoma
immune surveillance
nodal metastasis
tumor immune microenvironment
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11699/70238
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