To dissect the role of toll-like receptor (TLR) signalling and B cell survival/proliferating factors in the crosstalk between rheumatoid arthritis synovial fibroblasts (RASF) and B cells.

A BAFF/APRIL-dependent TLR3-stimulated pathway enhances the capacity of rheumatoid synovial fibroblasts to induce AID expression and Ig class-switching in B cells

Pitzalis, Costantino
2011-01-01

Abstract

To dissect the role of toll-like receptor (TLR) signalling and B cell survival/proliferating factors in the crosstalk between rheumatoid arthritis synovial fibroblasts (RASF) and B cells.
2011
Aged
Arthritis, Rheumatoid
B-Cell Activating Factor
B-Lymphocytes
Coculture Techniques
Cytidine Deaminase
Female
Fibroblasts
Humans
Immunoglobulin A
Immunoglobulin Class Switching
Immunoglobulin D
Immunoglobulin G
Lymphocyte Activation
Male
Middle Aged
Osteoarthritis
Polymerase Chain Reaction
RNA, Messenger
Signal Transduction
Skin
Synovial Membrane
Toll-Like Receptor 3
Tumor Necrosis Factor Ligand Superfamily Member 13
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11699/70514
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 101
  • ???jsp.display-item.citation.isi??? 92
social impact