To determine the relationship between synovial versus skin transcriptional/histological profiles in patients with active psoriatic arthritis (PsA) and explore mechanistic links between diseased tissue pathology and clinical outcomes.

IL-23 skin and joint profiling in psoriatic arthritis: novel perspectives in understanding clinical responses to IL-23 inhibitors

Pitzalis, Costantino
2021-01-01

Abstract

To determine the relationship between synovial versus skin transcriptional/histological profiles in patients with active psoriatic arthritis (PsA) and explore mechanistic links between diseased tissue pathology and clinical outcomes.
2021
arthritis
biological therapy
psoriatic
synovitis
Adult
Antirheumatic Agents
Arthritis, Psoriatic
Female
Gene Expression Profiling
Humans
Interleukin-17
Interleukin-23
Male
Middle Aged
Principal Component Analysis
Skin
Synovial Membrane
Synovitis
Treatment Outcome
Tumor Necrosis Factor Inhibitors
Ustekinumab
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11699/70624
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