To determine the relationship between synovial versus skin transcriptional/histological profiles in patients with active psoriatic arthritis (PsA) and explore mechanistic links between diseased tissue pathology and clinical outcomes.

IL-23 skin and joint profiling in psoriatic arthritis: novel perspectives in understanding clinical responses to IL-23 inhibitors

Pitzalis, Costantino
2021-01-01

Abstract

To determine the relationship between synovial versus skin transcriptional/histological profiles in patients with active psoriatic arthritis (PsA) and explore mechanistic links between diseased tissue pathology and clinical outcomes.
arthritis
biological therapy
psoriatic
synovitis
Adult
Antirheumatic Agents
Arthritis, Psoriatic
Female
Gene Expression Profiling
Humans
Interleukin-17
Interleukin-23
Male
Middle Aged
Principal Component Analysis
Skin
Synovial Membrane
Synovitis
Treatment Outcome
Tumor Necrosis Factor Inhibitors
Ustekinumab
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11699/70624
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 15
  • ???jsp.display-item.citation.isi??? 14
social impact