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To determine the relationship between synovial versus skin transcriptional/histological profiles in patients with active psoriatic arthritis (PsA) and explore mechanistic links between diseased tissue pathology and clinical outcomes.

IL-23 skin and joint profiling in psoriatic arthritis: novel perspectives in understanding clinical responses to IL-23 inhibitors

Pitzalis, Costantino
2021-01-01

Abstract

To determine the relationship between synovial versus skin transcriptional/histological profiles in patients with active psoriatic arthritis (PsA) and explore mechanistic links between diseased tissue pathology and clinical outcomes.
2021
Inglese
WOS:000641486900030
80
5
591
597
7
2-s2.0-85096979287
arthritis
biological therapy
psoriatic
synovitis
Adult
Antirheumatic Agents
Arthritis, Psoriatic
Female
Gene Expression Profiling
Humans
Interleukin-17
Interleukin-23
Male
Middle Aged
Principal Component Analysis
Skin
Synovial Membrane
Synovitis
Treatment Outcome
Tumor Necrosis Factor Inhibitors
Ustekinumab
Nerviani, Alessandra; Boutet, Marie-Astrid; Tan, Wang Sin Gina; Goldmann, Katriona; Purkayastha, Nirupam; Lajtos, Tamas Ajtos; Hands, Rebecca; Lewis, ...espandi
info:eu-repo/semantics/article
1 Contributo su Rivista::1.1 Articolo in rivista
262
10
open
1.1 Articolo in rivista
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11699/70624
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