To investigate the functional consequences of the single-nucleotide polymorphism rs4648889 in a putative enhancer upstream of the RUNX3 promoter associated with susceptibility to ankylosing spondylitis (AS).

Functional Genomic Analysis of a RUNX3 Polymorphism Associated With Ankylosing Spondylitis

Selmi, Carlo;
2021-01-01

Abstract

To investigate the functional consequences of the single-nucleotide polymorphism rs4648889 in a putative enhancer upstream of the RUNX3 promoter associated with susceptibility to ankylosing spondylitis (AS).
2021
Blotting, Western
CD8-Positive T-Lymphocytes
Core Binding Factor Alpha 3 Subunit
Electrophoretic Mobility Shift Assay
Enzyme-Linked Immunosorbent Assay
Gene Expression Regulation
Gene Knockdown Techniques
Genetic Predisposition to Disease
Humans
Ikaros Transcription Factor
Interferon Regulatory Factors
Interferon-gamma
Jurkat Cells
Mass Spectrometry
Mi-2 Nucleosome Remodeling and Deacetylase Complex
Polymorphism, Single Nucleotide
RNA, Messenger
RNA, Small Interfering
Retinoblastoma-Binding Protein 4
Reverse Transcriptase Polymerase Chain Reaction
Spondylitis, Ankylosing
Transcription Factors
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11699/70714
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