The SARS-CoV-2 pandemic has overwhelmed the treatment capacity of the health care systems during the highest viral diffusion rate. Patients reaching the emergency department had to be either hospitalized (inpatients) or discharged (outpatients). Still, the decision was taken based on the individual assessment of the actual clinical condition, without specific biomarkers to predict future improvement or deterioration, and discharged patients often returned to the hospital for aggravation of their condition. Here, we have developed a new combined approach of omics to identify factors that could distinguish coronavirus disease 19 (COVID-19) inpatients from outpatients.
A 'Multiomic' Approach of Saliva Metabolomics, Microbiota, and Serum Biomarkers to Assess the Need of Hospitalization in Coronavirus Disease 2019
Levi, Riccardo;Garlanda, Cecilia;Voza, Antonio;Azzolini, Elena;Cecconi, Maurizio;Aghemo, AlessioMembro del Collaboration Group
;Brescia, PaolaMembro del Collaboration Group
;Capucetti, AriannaMembro del Collaboration Group
;Carloni, SaraMembro del Collaboration Group
;Carnevale, SilviaMembro del Collaboration Group
;Lleo, AnaMembro del Collaboration Group
;Di Donato, RacheleMembro del Collaboration Group
;Digifico, ElisabethMembro del Collaboration Group
;Ferrari, ValentinaMembro del Collaboration Group
;Giugliano, SilviaMembro del Collaboration Group
;Lo Cascio, AntoninoMembro del Collaboration Group
;Mozzarelli, AlessandroMembro del Collaboration Group
;My, IlariaMembro del Collaboration Group
;Selmi, CarloMembro del Collaboration Group
;Voza, AntonioMembro del Collaboration Group
;Mantovani, Alberto;Politi, Letterio S;Rescigno, Maria
2022-01-01
Abstract
The SARS-CoV-2 pandemic has overwhelmed the treatment capacity of the health care systems during the highest viral diffusion rate. Patients reaching the emergency department had to be either hospitalized (inpatients) or discharged (outpatients). Still, the decision was taken based on the individual assessment of the actual clinical condition, without specific biomarkers to predict future improvement or deterioration, and discharged patients often returned to the hospital for aggravation of their condition. Here, we have developed a new combined approach of omics to identify factors that could distinguish coronavirus disease 19 (COVID-19) inpatients from outpatients.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
