PURPOSE OF REVIEW: The aim is to evaluate basic mechanisms, prevalence, risk factors, outcomes, and potential treatments of cardiovascular events (CVEs) in patients with community-acquired pneumonia (CAP). RECENT FINDINGS: In this review, we present a new model to evaluate the pathophysiology of cardiac disease in patients with pneumonia based on plaque-related events, such as acute myocardial infarction, versus plaque-unrelated events, such as arrhythmias and heart failure. CAP increases the risk for both plaque-related and plaque-unrelated events with an absolute rate of CVE across different cohorts that varies broadly from 10 to 30%. These complications may happen among both ambulatory patients and inpatients, either on admission or during hospitalization, and/or after discharge. CVEs represent a major cause for increased mortality in CAP patients, contributing to more than 30% of deaths at long-term follow-up. SUMMARY: From a clinical perspective, especially during the first 24 h after hospitalization, CAP patients should be tested for the probability to have or develop during hospitalization a cardiac event. From a research point of view, there is an urgent need to prospectively evaluate cardioprotective interventions.

Cardiac diseases complicating community-acquired pneumonia

S. Aliberti;
2014-01-01

Abstract

PURPOSE OF REVIEW: The aim is to evaluate basic mechanisms, prevalence, risk factors, outcomes, and potential treatments of cardiovascular events (CVEs) in patients with community-acquired pneumonia (CAP). RECENT FINDINGS: In this review, we present a new model to evaluate the pathophysiology of cardiac disease in patients with pneumonia based on plaque-related events, such as acute myocardial infarction, versus plaque-unrelated events, such as arrhythmias and heart failure. CAP increases the risk for both plaque-related and plaque-unrelated events with an absolute rate of CVE across different cohorts that varies broadly from 10 to 30%. These complications may happen among both ambulatory patients and inpatients, either on admission or during hospitalization, and/or after discharge. CVEs represent a major cause for increased mortality in CAP patients, contributing to more than 30% of deaths at long-term follow-up. SUMMARY: From a clinical perspective, especially during the first 24 h after hospitalization, CAP patients should be tested for the probability to have or develop during hospitalization a cardiac event. From a research point of view, there is an urgent need to prospectively evaluate cardioprotective interventions.
2014
Acute myocardial infarction
Arrhythmia
community-acquired pneumonia
Heart failure
Stroke
Arrhythmias
Cardiac
Cardiovascular Diseases
Community-Acquired Infections
Heart Failure
Hospitalization
Humans
Myocardial Infarction
Pneumonia
Prevalence
Risk Factors
Microbiology (medical)
Infectious Diseases
Medicine (all)
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11699/74353
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 42
  • ???jsp.display-item.citation.isi??? 39
social impact