Candida peritonitis is a potentially life-threatening infection after abdominal transplantation, although there is scant information regarding its incidence and outcome. We analysed the incidence rate and outcome of Candida peritonitis in 717 liver or pancreas transplant recipients. Five cases of Candida peritonitis were diagnosed, representing the second most frequent cause of invasive fungal infection in the cohort. The incidence rate of Candida peritonitis during the first 30days after transplantation was 6.5 cases/10 000 transplant days in pancreas recipients and 1.2 cases/10 000 transplant days in liver recipients (P=0.035). Four of the five patients received an echinocandin in combination with other antifungal. All patients were alive and with good graft function at 1-year follow-up. In our series, Candida peritonitis in liver and pancreas transplant recipients was not uncommon and had a good prognosis. © 2012 Blackwell Verlag GmbH.

Incidence and outcome of early Candida peritonitis after liver and pancreas transplantation

Bartoletti, Michele;
2013-01-01

Abstract

Candida peritonitis is a potentially life-threatening infection after abdominal transplantation, although there is scant information regarding its incidence and outcome. We analysed the incidence rate and outcome of Candida peritonitis in 717 liver or pancreas transplant recipients. Five cases of Candida peritonitis were diagnosed, representing the second most frequent cause of invasive fungal infection in the cohort. The incidence rate of Candida peritonitis during the first 30days after transplantation was 6.5 cases/10 000 transplant days in pancreas recipients and 1.2 cases/10 000 transplant days in liver recipients (P=0.035). Four of the five patients received an echinocandin in combination with other antifungal. All patients were alive and with good graft function at 1-year follow-up. In our series, Candida peritonitis in liver and pancreas transplant recipients was not uncommon and had a good prognosis. © 2012 Blackwell Verlag GmbH.
2013
Antifungal agents
Candida spp
Peritonitis
Adult
Aged
Antifungal Agents
Candida
Candidiasis
Cohort Studies
Female
Humans
Liver Transplantation
Male
Middle Aged
Pancreas Transplantation
Peritonitis
Postoperative Complications
Prospective Studies
2708
Infectious Diseases
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11699/74728
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