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EnglishCholecystokinin-8 like immunoreactivity (CCK-8 IR) was measured in different brain regions of rats with experimental liver cirrhosis. A statistically significant reduction of CCK-8 content was observed in the hypothalamus of cirrhotic rats. No significant modification of brain CCK fractionation pattern was observed in treated animals as compared to controls. The decrease of CCK-8 IR parallels the recently reported hypothalamic depletion of beta endorphin in cirrhotic rats confirming that central neuropeptides are affected by chronic liver failure.
| Titolo: | Brain cholecystokinin-8 immunoreactivity in rats with experimental liver cirrhosis |
| Autori: | |
| Data di pubblicazione: | 1983 |
| Rivista: | |
| Handle: | http://hdl.handle.net/11699/7477 |
| Appare nelle tipologie: | 1.1 Articolo in rivista |
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