A new study in zebrafish shows that Birc2, a member of the inhibitor of apoptosis (IAP) family, is required for endothelial cell survival. This discovery highlights an important in vivo function of this molecule and suggests potential avenues for the development of new antiangiogenic therapies. © 2007 Nature Publishing Group.

Building in resistance to endothelial cell death

Mazzone M.;
2007-01-01

Abstract

A new study in zebrafish shows that Birc2, a member of the inhibitor of apoptosis (IAP) family, is required for endothelial cell survival. This discovery highlights an important in vivo function of this molecule and suggests potential avenues for the development of new antiangiogenic therapies. © 2007 Nature Publishing Group.
2007
Angiogenesis Inhibitors
Animals
Cell Survival
Endothelium
Vascular
Inhibitor of Apoptosis Proteins
NF-kappa B
TNF Receptor-Associated Factor 2
Zebrafish
Zebrafish Proteins
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11699/83081
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