Obesity is a mild, long-lasting inflammatory disease and, as such, could increase the inflammatory burden of rheumatoid arthritis (RA). The study aim was to determine whether obesity represents a risk factor for a poor remission rate in RA patients requiring anti-tumor necrosis factor α (anti-TNFα) therapy for progressive and active disease despite treatment with methotrexate or other disease-modifying antirheumatic drugs.

Obesity and reduction of the response rate to anti-tumor necrosis factor α in rheumatoid arthritis: an approach to a personalized medicine

Gremese, Elisa;
2013-01-01

Abstract

Obesity is a mild, long-lasting inflammatory disease and, as such, could increase the inflammatory burden of rheumatoid arthritis (RA). The study aim was to determine whether obesity represents a risk factor for a poor remission rate in RA patients requiring anti-tumor necrosis factor α (anti-TNFα) therapy for progressive and active disease despite treatment with methotrexate or other disease-modifying antirheumatic drugs.
2013
Aged
Antibodies
Monoclonal
Antibodies
Monoclonal
Humanized
Antirheumatic Agents
Arthritis
Rheumatoid
Dose-Response Relationship
Drug
Female
Humans
Immunoglobulin G
Individualized Medicine
Longitudinal Studies
Male
Middle Aged
Obesity
Receptors
Tumor Necrosis Factor
Registries
Remission Induction
Treatment Outcome
Tumor Necrosis Factor-alpha
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11699/85570
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