Chemokines are important components of cancer-related inflammation. In this issue of Cancer Cell, Chen et al. report that the chemokine CCL18, produced by tumor-associated macrophages, promotes malignant behavior and correlates with metastasis in human breast cancer. Unexpectedly, PITPNM3/Nir1, a molecule unrelated to chemokine receptors, was identified as its elusive receptor.

Chemokines and cancer: a fatal attraction

R. Bonecchi;
2011

Abstract

Chemokines are important components of cancer-related inflammation. In this issue of Cancer Cell, Chen et al. report that the chemokine CCL18, produced by tumor-associated macrophages, promotes malignant behavior and correlates with metastasis in human breast cancer. Unexpectedly, PITPNM3/Nir1, a molecule unrelated to chemokine receptors, was identified as its elusive receptor.
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11699/9484
Citazioni
  • ???jsp.display-item.citation.pmc??? 35
  • Scopus 62
  • ???jsp.display-item.citation.isi??? 56
social impact