IntroductionCefiderocol is a new siderophore cephalosporin designed to be active against extensively resistant Gram-negative bacteria; however, clinical studies are limited to complicated urinary tract infections, pneumonia, and intra-abdominal infections. To date, no data are available on neurosurgical site infections.Case presentationWe present a case of a patient successfully cured with Cefiderocol for a neurosurgical site infection due to extensively resistant P. aeruginosa, who had failed a previous treatment based on combined antimicrobial therapy and right parietal bone excision.ConclusionsCefiderocol is a promising antibiotic for complicated infections due to multidrug resistant gram-negative bacteria.

Recurrent neurosurgical site infection by extensively drug-resistant P. aeruginosa treated with cefiderocol: a case report and literature review

Bavaro, Davide Fiore;
2020-01-01

Abstract

IntroductionCefiderocol is a new siderophore cephalosporin designed to be active against extensively resistant Gram-negative bacteria; however, clinical studies are limited to complicated urinary tract infections, pneumonia, and intra-abdominal infections. To date, no data are available on neurosurgical site infections.Case presentationWe present a case of a patient successfully cured with Cefiderocol for a neurosurgical site infection due to extensively resistant P. aeruginosa, who had failed a previous treatment based on combined antimicrobial therapy and right parietal bone excision.ConclusionsCefiderocol is a promising antibiotic for complicated infections due to multidrug resistant gram-negative bacteria.
2020
Pseudomonas Aeruginosa
Staphylococcus aureus
Cefiderocol
antimicrobial resistance
hospital acquired infections
surgical site infections
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11699/97748
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