Inhibition of tumor angiogenesis and growth by a small-molecule multi-FGF receptor blocker with allosteric properties
2013-01-01 Bono, F.; De Smet, F.; Herbert, C.; De Bock, K.; Georgiadou, M.; Fons, P.; Tjwa, M.; Alcouffe, C.; Ny, A.; Bianciotto, M.; Jonckx, B.; Murakami, M.; Lanahan, A. A.; Michielsen, C.; Sibrac, D.; Dol-Gleizes, F.; Mazzone, M.; Zacchigna, S.; Herault, J. -P.; Fischer, C.; Rigon, P.; Ruiz de Almodovar, C.; Claes, F.; Blanc, I.; Poesen, K.; Zhang, J.; Segura, I.; Gueguen, G.; Bordes, M. -F.; Lambrechts, D.; Broussy, R.; van de Wouwer, M.; Michaux, C.; Shimada, T.; Jean, I.; Blacher, S.; Noel, A.; Motte, P.; Rom, E.; Rakic, J. -M.; Katsuma, S.; Schaeffer, P.; Yayon, A.; Van Schepdael, A.; Schwalbe, H.; Gervasio, F. L.; Carmeliet, G.; Rozensky, J.; Dewerchin, M.; Simons, M.; Christopoulos, A.; Herbert, J. -M.; Carmeliet, P.
Immunity, hypoxia, and metabolism–the ménage à trois of cancer: Implications for immunotherapy
2020-01-01 Riera-Domingo, C.; Audige, A.; Granja, S.; Cheng, W. -C.; Ho, P. -C.; Baltazar, F.; Stockmann, C.; Mazzone, M.
PHD2 Targeting Overcomes Breast Cancer Cell Death upon Glucose Starvation in a PP2A/B55α-Mediated Manner
2017-01-01 Di Conza, G.; Trusso Cafarello, S.; Zheng, X.; Zhang, Q.; Mazzone, M.
Genetic Deficiency in Plasma Protein HRG Enhances Tumor Growth and Metastasis by Exacerbating Immune Escape and Vessel Abnormalization
2012-01-01 Tugues, S; Honjo, S; Konig, C; Noguer, O; Hedlund, M; Botling, J; Deschoemaeker, S; Wenes, M; Rolny, C; Jahnen-Dechent, W; Mazzone, M; Claesson-Welsh, L
Renal CD133+/CD73+ Progenitors Produce Erythropoietin under Hypoxia and Prolyl Hydroxylase Inhibition
2013-01-01 Benedetta, Bussolati; Carola, Lauritano; Aldo, Moggio; Federica, Collino; Mazzone, M.; Giovanni, Camussi
Blood Vessel Proximity Shapes Cancer Cell Metabolism
2019-01-01 Virga, F.; Ehling, M.; Mazzone, M.
The therapeutic potential of hepatocyte growth factor to sensitize ovarian cancer cells to cisplatin and paclitaxel in vivo
2007-01-01 Bardella, C; Dettori, D; Olivero, M; Coltella, N; Mazzone, M; Di Renzo, Mf
The mTOR and PP2A Pathways Regulate PHD2 Phosphorylation to Fine-Tune HIF1α Levels and Colorectal Cancer Cell Survival under Hypoxia
2017-01-01 Di Conza, G.; Trusso Cafarello, S.; Loroch, S.; Mennerich, D.; Deschoemaeker, S.; Di Matteo, M.; Ehling, M.; Gevaert, K.; Prenen, H.; Zahedi, R. P.; Sickmann, A.; Kietzmann, T.; Moretti, F.; Mazzone, M.
VEGF pathway genetic variants as biomarkers of treatment outcome with bevacizumab: an analysis of data from the AViTA and AVOREN randomised trials
2012-01-01 Lambrechts, D; Claes, B; Delmar, P; Reumers, J; Mazzone, M; Yesilyurt, Bt; Devlieger, R; Verslype, C; Tejpar, S; Wildiers, H; de Haas, S; Carmeliet, P; Scherer, Sj; Van Cutsem, E
Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism
2008-01-01 Aragones, J.; Schneider, M.; Van Geyte, K.; Fraisl, P.; Dresselaers, T.; Mazzone, M.; Dirkx, R.; Zacchigna, S.; Lemieux, H.; Jeoung, N. H.; Lambrechts, D.; Bishop, T.; Lafuste, P.; Diez-Juan, A.; Harten, S. K.; Van Noten, P.; De Bock, K.; Willam, C.; Tjwa, M.; Grosfeld, A.; Navet, R.; Moons, L.; Vandendriessche, T.; Deroose, C.; Wijeyekoon, B.; Nuyts, J.; Jordan, B.; Silasi-Mansat, R.; Lupu, F.; Dewerchin, M.; Pugh, C.; Salmon, P.; Mortelmans, L.; Gallez, B.; Gorus, F.; Buyse, J.; Sluse, F.; Harris, R. A.; Gnaiger, E.; Hespel, P.; Van Hecke, P.; Schuit, F.; Van Veldhoven, P.; Ratcliffe, P.; Baes, M.; Maxwell, P.; Carmeliet, P.
Hypoxia promotes invasive growth by transcriptional activation of the met protooncogene
2003-01-01 Selma, Pennacchietti; Paolo, Michieli; Galluzzo, M.; Mazzone, M.; Silvia, Giordano; Paolo, Comoglio
Prolyl Hydroxylases in fight or flight
2012-01-01 Henze, At; Leite de Oliveira, R; Mazzone, M
Oncogenic p95HER2/611CTF primes human breast epithelial cells for metabolic stress-induced down-regulation of FLIP and activation of TRAIL-R/Caspase-8-dependent apoptosis
2017-01-01 Martin-Perez, R.; Yerbes, R.; Mora-Molina, R.; Cano-Gonzalez, A.; Arribas, J.; Mazzone, M.; Lopez-Rivas, A.; Palacios, C.
How metabolism bridles cytotoxic CD8+ T cells through epigenetic modifications
2021-01-01 Van Acker, H. H.; Ma, S.; Scolaro, T.; Kaech, S. M.; Mazzone, M.
Stroma-derived miR-214 coordinates tumor dissemination
2023-01-01 Orso, F.; Virga, F.; Dettori, D.; Dalmasso, A.; Paradzik, M.; Savino, A.; Pomatto, M. A. C.; Quirico, L.; Cucinelli, S.; Coco, M.; Mareschi, K.; Fagioli, F.; Salmena, L.; Camussi, G.; Provero, P.; Poli, V.; Mazzone, M.; Pandolfi, P. P.; Taverna, D.
Caspase-8 modulates physiological and pathological angiogenesis during retina development
2019-01-01 Tisch, N.; Freire-Valls, A.; Yerbes, R.; Paredes, I.; Porta, S. L.; Wang, X.; Martin-Perez, R.; Castro, L.; Wong, W. W. -L.; Coultas, L.; Strilic, B.; Grone, H. -J.; Hielscher, T.; Mogler, C.; Adams, R. H.; Heiduschka, P.; Claesson-Welsh, L.; Mazzone, M.; Lopez-Rivas, A.; Schmidt, T.; Augustin, H. G.; De Almodovar, C. R.
FXR agonist obeticholic acid reduces hepatic inflammation and fibrosis in a rat model of toxic cirrhosis
2016-01-01 Verbeke, L.; Mannaerts, I.; Schierwagen, R.; Govaere, O.; Klein, S.; Vander Elst, I.; Windmolders, P.; Farre, R.; Wenes, M.; Mazzone, M.; Nevens, F.; Van Grunsven, L. A.; Trebicka, J.; Laleman, W.
Antiangiogenic therapy, hypoxia, and metastasis: risky liaisons, or not?
2011-01-01 De Bock, K; Mazzone, M; Carmeliet, P
Metabolic traits ruling the specificity of the immune response in different cancer types
2021-01-01 Flerin, N. C.; Cappellesso, F.; Pretto, S.; Mazzone, M.
FLT1 and its ligands VEGFB and PlGF: Drug targets for anti-angiogenic therapy?
2008-01-01 Fischer, C.; Mazzone, M.; Jonckx, B.; Carmeliet, P.
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Inhibition of tumor angiogenesis and growth by a small-molecule multi-FGF receptor blocker with allosteric properties | 1-gen-2013 | Bono, F.; De Smet, F.; Herbert, C.; De Bock, K.; Georgiadou, M.; Fons, P.; Tjwa, M.; Alcouffe, C.; Ny, A.; Bianciotto, M.; Jonckx, B.; Murakami, M.; Lanahan, A. A.; Michielsen, C.; Sibrac, D.; Dol-Gleizes, F.; Mazzone, M.; Zacchigna, S.; Herault, J. -P.; Fischer, C.; Rigon, P.; Ruiz de Almodovar, C.; Claes, F.; Blanc, I.; Poesen, K.; Zhang, J.; Segura, I.; Gueguen, G.; Bordes, M. -F.; Lambrechts, D.; Broussy, R.; van de Wouwer, M.; Michaux, C.; Shimada, T.; Jean, I.; Blacher, S.; Noel, A.; Motte, P.; Rom, E.; Rakic, J. -M.; Katsuma, S.; Schaeffer, P.; Yayon, A.; Van Schepdael, A.; Schwalbe, H.; Gervasio, F. L.; Carmeliet, G.; Rozensky, J.; Dewerchin, M.; Simons, M.; Christopoulos, A.; Herbert, J. -M.; Carmeliet, P. | |
| Immunity, hypoxia, and metabolism–the ménage à trois of cancer: Implications for immunotherapy | 1-gen-2020 | Riera-Domingo, C.; Audige, A.; Granja, S.; Cheng, W. -C.; Ho, P. -C.; Baltazar, F.; Stockmann, C.; Mazzone, M. | |
| PHD2 Targeting Overcomes Breast Cancer Cell Death upon Glucose Starvation in a PP2A/B55α-Mediated Manner | 1-gen-2017 | Di Conza, G.; Trusso Cafarello, S.; Zheng, X.; Zhang, Q.; Mazzone, M. | |
| Genetic Deficiency in Plasma Protein HRG Enhances Tumor Growth and Metastasis by Exacerbating Immune Escape and Vessel Abnormalization | 1-gen-2012 | Tugues, S; Honjo, S; Konig, C; Noguer, O; Hedlund, M; Botling, J; Deschoemaeker, S; Wenes, M; Rolny, C; Jahnen-Dechent, W; Mazzone, M; Claesson-Welsh, L | |
| Renal CD133+/CD73+ Progenitors Produce Erythropoietin under Hypoxia and Prolyl Hydroxylase Inhibition | 1-gen-2013 | Benedetta, Bussolati; Carola, Lauritano; Aldo, Moggio; Federica, Collino; Mazzone, M.; Giovanni, Camussi | |
| Blood Vessel Proximity Shapes Cancer Cell Metabolism | 1-gen-2019 | Virga, F.; Ehling, M.; Mazzone, M. | |
| The therapeutic potential of hepatocyte growth factor to sensitize ovarian cancer cells to cisplatin and paclitaxel in vivo | 1-gen-2007 | Bardella, C; Dettori, D; Olivero, M; Coltella, N; Mazzone, M; Di Renzo, Mf | |
| The mTOR and PP2A Pathways Regulate PHD2 Phosphorylation to Fine-Tune HIF1α Levels and Colorectal Cancer Cell Survival under Hypoxia | 1-gen-2017 | Di Conza, G.; Trusso Cafarello, S.; Loroch, S.; Mennerich, D.; Deschoemaeker, S.; Di Matteo, M.; Ehling, M.; Gevaert, K.; Prenen, H.; Zahedi, R. P.; Sickmann, A.; Kietzmann, T.; Moretti, F.; Mazzone, M. | |
| VEGF pathway genetic variants as biomarkers of treatment outcome with bevacizumab: an analysis of data from the AViTA and AVOREN randomised trials | 1-gen-2012 | Lambrechts, D; Claes, B; Delmar, P; Reumers, J; Mazzone, M; Yesilyurt, Bt; Devlieger, R; Verslype, C; Tejpar, S; Wildiers, H; de Haas, S; Carmeliet, P; Scherer, Sj; Van Cutsem, E | |
| Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism | 1-gen-2008 | Aragones, J.; Schneider, M.; Van Geyte, K.; Fraisl, P.; Dresselaers, T.; Mazzone, M.; Dirkx, R.; Zacchigna, S.; Lemieux, H.; Jeoung, N. H.; Lambrechts, D.; Bishop, T.; Lafuste, P.; Diez-Juan, A.; Harten, S. K.; Van Noten, P.; De Bock, K.; Willam, C.; Tjwa, M.; Grosfeld, A.; Navet, R.; Moons, L.; Vandendriessche, T.; Deroose, C.; Wijeyekoon, B.; Nuyts, J.; Jordan, B.; Silasi-Mansat, R.; Lupu, F.; Dewerchin, M.; Pugh, C.; Salmon, P.; Mortelmans, L.; Gallez, B.; Gorus, F.; Buyse, J.; Sluse, F.; Harris, R. A.; Gnaiger, E.; Hespel, P.; Van Hecke, P.; Schuit, F.; Van Veldhoven, P.; Ratcliffe, P.; Baes, M.; Maxwell, P.; Carmeliet, P. | |
| Hypoxia promotes invasive growth by transcriptional activation of the met protooncogene | 1-gen-2003 | Selma, Pennacchietti; Paolo, Michieli; Galluzzo, M.; Mazzone, M.; Silvia, Giordano; Paolo, Comoglio | |
| Prolyl Hydroxylases in fight or flight | 1-gen-2012 | Henze, At; Leite de Oliveira, R; Mazzone, M | |
| Oncogenic p95HER2/611CTF primes human breast epithelial cells for metabolic stress-induced down-regulation of FLIP and activation of TRAIL-R/Caspase-8-dependent apoptosis | 1-gen-2017 | Martin-Perez, R.; Yerbes, R.; Mora-Molina, R.; Cano-Gonzalez, A.; Arribas, J.; Mazzone, M.; Lopez-Rivas, A.; Palacios, C. | |
| How metabolism bridles cytotoxic CD8+ T cells through epigenetic modifications | 1-gen-2021 | Van Acker, H. H.; Ma, S.; Scolaro, T.; Kaech, S. M.; Mazzone, M. | |
| Stroma-derived miR-214 coordinates tumor dissemination | 1-gen-2023 | Orso, F.; Virga, F.; Dettori, D.; Dalmasso, A.; Paradzik, M.; Savino, A.; Pomatto, M. A. C.; Quirico, L.; Cucinelli, S.; Coco, M.; Mareschi, K.; Fagioli, F.; Salmena, L.; Camussi, G.; Provero, P.; Poli, V.; Mazzone, M.; Pandolfi, P. P.; Taverna, D. | |
| Caspase-8 modulates physiological and pathological angiogenesis during retina development | 1-gen-2019 | Tisch, N.; Freire-Valls, A.; Yerbes, R.; Paredes, I.; Porta, S. L.; Wang, X.; Martin-Perez, R.; Castro, L.; Wong, W. W. -L.; Coultas, L.; Strilic, B.; Grone, H. -J.; Hielscher, T.; Mogler, C.; Adams, R. H.; Heiduschka, P.; Claesson-Welsh, L.; Mazzone, M.; Lopez-Rivas, A.; Schmidt, T.; Augustin, H. G.; De Almodovar, C. R. | |
| FXR agonist obeticholic acid reduces hepatic inflammation and fibrosis in a rat model of toxic cirrhosis | 1-gen-2016 | Verbeke, L.; Mannaerts, I.; Schierwagen, R.; Govaere, O.; Klein, S.; Vander Elst, I.; Windmolders, P.; Farre, R.; Wenes, M.; Mazzone, M.; Nevens, F.; Van Grunsven, L. A.; Trebicka, J.; Laleman, W. | |
| Antiangiogenic therapy, hypoxia, and metastasis: risky liaisons, or not? | 1-gen-2011 | De Bock, K; Mazzone, M; Carmeliet, P | |
| Metabolic traits ruling the specificity of the immune response in different cancer types | 1-gen-2021 | Flerin, N. C.; Cappellesso, F.; Pretto, S.; Mazzone, M. | |
| FLT1 and its ligands VEGFB and PlGF: Drug targets for anti-angiogenic therapy? | 1-gen-2008 | Fischer, C.; Mazzone, M.; Jonckx, B.; Carmeliet, P. |
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