Blockade of Glutamine Synthetase Enhances Inflammatory Response in Microglial Cells
2017-01-01 Palmieri, E. M.; Menga, A.; Lebrun, A.; Hooper, D. C.; Butterfield, D. A.; Mazzone, M.; Castegna, A.
A collaborative synthetase
2023-01-01 Mazzone, M.; Castegna, A.
Reprogramming of Amino Acid Transporters to Support Aspartate and Glutamate Dependency Sustains Endocrine Resistance in Breast Cancer
2019-01-01 Bacci, M.; Lorito, N.; Ippolito, L.; Ramazzotti, M.; Luti, S.; Romagnoli, S.; Parri, M.; Bianchini, F.; Cappellesso, F.; Virga, F.; Gao, Q.; Simoes, B. M.; Marangoni, E.; Martin, L. -A.; Comito, G.; Ferracin, M.; Giannoni, E.; Mazzone, M.; Chiarugi, P.; Morandi, A.
The reciprocal function and regulation of tumor vessels and immune cells offers new therapeutic opportunities in cancer
2018-01-01 Missiaen, R.; Mazzone, M.; Bergers, G.
Deficiency of the oxygen sensor prolyl hydroxylase 1 attenuates hypercholesterolaemia, atherosclerosis, and hyperglycaemia
2016-01-01 Marsch, E.; Demandt, J. A. F.; Theelen, T. L.; Tullemans, B. M. E.; Wouters, K.; Boon, M. R.; Van Dijk, T. H.; Gijbels, M. J.; Dubois, L. J.; Meex, S. J. R.; Mazzone, M.; Hung, G.; Fisher, E. A.; Biessen, E. A. L.; Daemen, M. J. A. P.; Rensen, P. C. N.; Carmeliet, P.; Groen, A. K.; Sluimer, J. C.
Prolyl hydroxylase 2 inactivation enhances glycogen storage and promotes excessive neutrophilic responses
2017-01-01 Sadiku, P.; Willson, J. A.; Dickinson, R. S.; Murphy, F.; Harris, A. J.; Lewis, A.; Sammut, D.; Mirchandani, A. S.; Ryan, E.; Watts, E. R.; Thompson, A. A. R.; Marriott, H. M.; Dockrell, D. H.; Taylor, C. T.; Schneider, M.; Maxwell, P. H.; Chilvers, E. R.; Mazzone, M.; Moral, V.; Pugh, C. W.; Ratcliffe, P. J.; Schofield, C. J.; Ghesquiere, B.; Carmeliet, P.; Whyte, M. K. B.; Walmsley, S. R.
Tanycytic VEGF-A boosts blood-hypothalamus barrier plasticity and access of metabolic signals to the arcuate nucleus in response to fasting
2013-01-01 Langlet, F.; Levin, B. E.; Luquet, S.; Mazzone, M.; Messina, A.; Dunn-Meynell, A. A.; Balland, E.; Lacombe, A.; Mazur, D.; Carmeliet, P.; Bouret, S. G.; Prevot, V.; Dehouck, B.
Drug discovery: A lifeline for suffocating tissues
2008-01-01 Mazzone, M.; Carmeliet, P.
Neutrophilic HGF-MET Signalling Exacerbates Intestinal Inflammation
2020-01-01 Stakenborg, M.; Verstockt, B.; Meroni, E.; Goverse, G.; De Simone, V.; Verstockt, S.; Di Matteo, M.; Czarnewski, P.; Villablanca, E. J.; Ferrante, M.; Boeckxstaens, G. E.; Mazzone, M.; Vermeire, S.; Matteoli, G.
Differential effects of trp53 alterations in murine colorectal cancer
2021-01-01 Betzler, A. M.; Nanduri, L. K.; Hissa, B.; Blickensdorfer, L.; Muders, M. H.; Roy, J.; Jesinghaus, M.; Steiger, K.; Weichert, W.; Kloor, M.; Klink, B.; Schroeder, M.; Mazzone, M.; Weitz, J.; Reissfelder, C.; Rahbari, N. N.; Scholch, S.
Inhibition of prolyl hydroxylase domain proteins selectively enhances venous thrombus neovascularisation
2018-01-01 Grover, S. P.; Saha, P.; Humphries, J.; Lyons, O. T.; Patel, A. S.; Serneels, J.; Modarai, B.; Mazzone, M.; Smith, A.
Tumor vessel co-option probed by single-cell analysis
2021-01-01 Teuwen, L. -A.; De Rooij, L. P. M. H.; Cuypers, A.; Rohlenova, K.; Dumas, S. J.; Garcia-Caballero, M.; Meta, E.; Amersfoort, J.; Taverna, F.; Becker, L. M.; Veiga, N.; Cantelmo, A. R.; Geldhof, V.; Conchinha, N. V.; Kalucka, J.; Treps, L.; Conradi, L. -C.; Khan, S.; Karakach, T. K.; Soenen, S.; Vinckier, S.; Schoonjans, L.; Eelen, G.; Van Laere, S.; Dewerchin, M.; Dirix, L.; Mazzone, M.; Luo, Y.; Vermeulen, P.; Carmeliet, P.
Loss of Caveolin-1 in Metastasis-Associated Macrophages Drives Lung Metastatic Growth through Increased Angiogenesis
2017-01-01 Celus, W.; Di Conza, G.; Oliveira, A. I.; Ehling, M.; Costa, B. M.; Wenes, M.; Mazzone, M.
The tumor suppressor semaphorin 3B triggers a prometastatic program mediated by interleukin 8 and the tumor microenvironment
2008-01-01 Rolny, C; Capparuccia, Lorena; Casazza, Andrea; Mazzone, M; Vallario, A; Cignetti, Alessandro; Medico, Enzo; Carmeliet, P; Comoglio, Paolo; Tamagnone, Luca
Betulinic Acid Hydroxamate is Neuroprotective and Induces Protein Phosphatase 2A-Dependent HIF-1α Stabilization and Post-transcriptional Dephosphorylation of Prolyl Hydrolase 2
2021-01-01 Prados, M. E.; Correa-Saez, A.; Unciti-Broceta, J. D.; Garrido-Rodriguez, M.; Jimenez-Jimenez, C.; Mazzone, M.; Minassi, A.; Appendino, G.; Calzado, M. A.; Munoz, E.
Preclinical and clinical evaluation of MET functions in cancer cells and in the tumor stroma
2016-01-01 Finisguerra, V.; Prenen, H.; Mazzone, M.
Regulation of Angiogenesis by Oxygen and Metabolism
2009-01-01 Fraisl, P.; Mazzone, M.; Schmidt, T.; Carmeliet, P.
Systemic and Targeted Delivery of Semaphorin 3A Inhibits Tumor Angiogenesis and Progression in Mouse Tumor Models
2011-01-01 Casazza, Andrea; Fu, X; Johansson, I; Capparuccia, Lorena; Andersson, F; Giustacchini, A; Squadrito, Ml; Venneri, Ma; Mazzone, M; Larsson, E; Carmeliet, P; De Palma, M; Naldini, Luigi; Tamagnone, Luca; Rolny, C.
Macrophage skewing by Phd2 haplodeficiency prevents ischaemia by inducing arteriogenesis
2011-01-01 Takeda, Y.; Costa, S.; Delamarre, E.; Roncal, C.; Leite De Oliveira, R.; Squadrito, M. L.; Finisguerra, V.; Deschoemaeker, S.; Bruyere, F.; Wenes, M.; Hamm, A.; Serneels, J.; Magat, J.; Bhattacharyya, T.; Anisimov, A.; Jordan, B. F.; Alitalo, K.; Maxwell, P.; Gallez, B.; Zhuang, Z. W.; Saito, Y.; Simons, M.; De Palma, M.; Mazzone, M.
Anti-PlGF Inhibits Growth of VEGF(R)-Inhibitor-Resistant Tumors without Affecting Healthy Vessels
2007-01-01 Fischer, C.; Jonckx, B.; Mazzone, M.; Zacchigna, S.; Loges, S.; Pattarini, L.; Chorianopoulos, E.; Liesenborghs, L.; Koch, M.; De Mol, M.; Autiero, M.; Wyns, S.; Plaisance, S.; Moons, L.; van Rooijen, N.; Giacca, M.; Stassen, J. -M.; Dewerchin, M.; Collen, D.; Carmeliet, P.
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Blockade of Glutamine Synthetase Enhances Inflammatory Response in Microglial Cells | 1-gen-2017 | Palmieri, E. M.; Menga, A.; Lebrun, A.; Hooper, D. C.; Butterfield, D. A.; Mazzone, M.; Castegna, A. | |
| A collaborative synthetase | 1-gen-2023 | Mazzone, M.; Castegna, A. | |
| Reprogramming of Amino Acid Transporters to Support Aspartate and Glutamate Dependency Sustains Endocrine Resistance in Breast Cancer | 1-gen-2019 | Bacci, M.; Lorito, N.; Ippolito, L.; Ramazzotti, M.; Luti, S.; Romagnoli, S.; Parri, M.; Bianchini, F.; Cappellesso, F.; Virga, F.; Gao, Q.; Simoes, B. M.; Marangoni, E.; Martin, L. -A.; Comito, G.; Ferracin, M.; Giannoni, E.; Mazzone, M.; Chiarugi, P.; Morandi, A. | |
| The reciprocal function and regulation of tumor vessels and immune cells offers new therapeutic opportunities in cancer | 1-gen-2018 | Missiaen, R.; Mazzone, M.; Bergers, G. | |
| Deficiency of the oxygen sensor prolyl hydroxylase 1 attenuates hypercholesterolaemia, atherosclerosis, and hyperglycaemia | 1-gen-2016 | Marsch, E.; Demandt, J. A. F.; Theelen, T. L.; Tullemans, B. M. E.; Wouters, K.; Boon, M. R.; Van Dijk, T. H.; Gijbels, M. J.; Dubois, L. J.; Meex, S. J. R.; Mazzone, M.; Hung, G.; Fisher, E. A.; Biessen, E. A. L.; Daemen, M. J. A. P.; Rensen, P. C. N.; Carmeliet, P.; Groen, A. K.; Sluimer, J. C. | |
| Prolyl hydroxylase 2 inactivation enhances glycogen storage and promotes excessive neutrophilic responses | 1-gen-2017 | Sadiku, P.; Willson, J. A.; Dickinson, R. S.; Murphy, F.; Harris, A. J.; Lewis, A.; Sammut, D.; Mirchandani, A. S.; Ryan, E.; Watts, E. R.; Thompson, A. A. R.; Marriott, H. M.; Dockrell, D. H.; Taylor, C. T.; Schneider, M.; Maxwell, P. H.; Chilvers, E. R.; Mazzone, M.; Moral, V.; Pugh, C. W.; Ratcliffe, P. J.; Schofield, C. J.; Ghesquiere, B.; Carmeliet, P.; Whyte, M. K. B.; Walmsley, S. R. | |
| Tanycytic VEGF-A boosts blood-hypothalamus barrier plasticity and access of metabolic signals to the arcuate nucleus in response to fasting | 1-gen-2013 | Langlet, F.; Levin, B. E.; Luquet, S.; Mazzone, M.; Messina, A.; Dunn-Meynell, A. A.; Balland, E.; Lacombe, A.; Mazur, D.; Carmeliet, P.; Bouret, S. G.; Prevot, V.; Dehouck, B. | |
| Drug discovery: A lifeline for suffocating tissues | 1-gen-2008 | Mazzone, M.; Carmeliet, P. | |
| Neutrophilic HGF-MET Signalling Exacerbates Intestinal Inflammation | 1-gen-2020 | Stakenborg, M.; Verstockt, B.; Meroni, E.; Goverse, G.; De Simone, V.; Verstockt, S.; Di Matteo, M.; Czarnewski, P.; Villablanca, E. J.; Ferrante, M.; Boeckxstaens, G. E.; Mazzone, M.; Vermeire, S.; Matteoli, G. | |
| Differential effects of trp53 alterations in murine colorectal cancer | 1-gen-2021 | Betzler, A. M.; Nanduri, L. K.; Hissa, B.; Blickensdorfer, L.; Muders, M. H.; Roy, J.; Jesinghaus, M.; Steiger, K.; Weichert, W.; Kloor, M.; Klink, B.; Schroeder, M.; Mazzone, M.; Weitz, J.; Reissfelder, C.; Rahbari, N. N.; Scholch, S. | |
| Inhibition of prolyl hydroxylase domain proteins selectively enhances venous thrombus neovascularisation | 1-gen-2018 | Grover, S. P.; Saha, P.; Humphries, J.; Lyons, O. T.; Patel, A. S.; Serneels, J.; Modarai, B.; Mazzone, M.; Smith, A. | |
| Tumor vessel co-option probed by single-cell analysis | 1-gen-2021 | Teuwen, L. -A.; De Rooij, L. P. M. H.; Cuypers, A.; Rohlenova, K.; Dumas, S. J.; Garcia-Caballero, M.; Meta, E.; Amersfoort, J.; Taverna, F.; Becker, L. M.; Veiga, N.; Cantelmo, A. R.; Geldhof, V.; Conchinha, N. V.; Kalucka, J.; Treps, L.; Conradi, L. -C.; Khan, S.; Karakach, T. K.; Soenen, S.; Vinckier, S.; Schoonjans, L.; Eelen, G.; Van Laere, S.; Dewerchin, M.; Dirix, L.; Mazzone, M.; Luo, Y.; Vermeulen, P.; Carmeliet, P. | |
| Loss of Caveolin-1 in Metastasis-Associated Macrophages Drives Lung Metastatic Growth through Increased Angiogenesis | 1-gen-2017 | Celus, W.; Di Conza, G.; Oliveira, A. I.; Ehling, M.; Costa, B. M.; Wenes, M.; Mazzone, M. | |
| The tumor suppressor semaphorin 3B triggers a prometastatic program mediated by interleukin 8 and the tumor microenvironment | 1-gen-2008 | Rolny, C; Capparuccia, Lorena; Casazza, Andrea; Mazzone, M; Vallario, A; Cignetti, Alessandro; Medico, Enzo; Carmeliet, P; Comoglio, Paolo; Tamagnone, Luca | |
| Betulinic Acid Hydroxamate is Neuroprotective and Induces Protein Phosphatase 2A-Dependent HIF-1α Stabilization and Post-transcriptional Dephosphorylation of Prolyl Hydrolase 2 | 1-gen-2021 | Prados, M. E.; Correa-Saez, A.; Unciti-Broceta, J. D.; Garrido-Rodriguez, M.; Jimenez-Jimenez, C.; Mazzone, M.; Minassi, A.; Appendino, G.; Calzado, M. A.; Munoz, E. | |
| Preclinical and clinical evaluation of MET functions in cancer cells and in the tumor stroma | 1-gen-2016 | Finisguerra, V.; Prenen, H.; Mazzone, M. | |
| Regulation of Angiogenesis by Oxygen and Metabolism | 1-gen-2009 | Fraisl, P.; Mazzone, M.; Schmidt, T.; Carmeliet, P. | |
| Systemic and Targeted Delivery of Semaphorin 3A Inhibits Tumor Angiogenesis and Progression in Mouse Tumor Models | 1-gen-2011 | Casazza, Andrea; Fu, X; Johansson, I; Capparuccia, Lorena; Andersson, F; Giustacchini, A; Squadrito, Ml; Venneri, Ma; Mazzone, M; Larsson, E; Carmeliet, P; De Palma, M; Naldini, Luigi; Tamagnone, Luca; Rolny, C. | |
| Macrophage skewing by Phd2 haplodeficiency prevents ischaemia by inducing arteriogenesis | 1-gen-2011 | Takeda, Y.; Costa, S.; Delamarre, E.; Roncal, C.; Leite De Oliveira, R.; Squadrito, M. L.; Finisguerra, V.; Deschoemaeker, S.; Bruyere, F.; Wenes, M.; Hamm, A.; Serneels, J.; Magat, J.; Bhattacharyya, T.; Anisimov, A.; Jordan, B. F.; Alitalo, K.; Maxwell, P.; Gallez, B.; Zhuang, Z. W.; Saito, Y.; Simons, M.; De Palma, M.; Mazzone, M. | |
| Anti-PlGF Inhibits Growth of VEGF(R)-Inhibitor-Resistant Tumors without Affecting Healthy Vessels | 1-gen-2007 | Fischer, C.; Jonckx, B.; Mazzone, M.; Zacchigna, S.; Loges, S.; Pattarini, L.; Chorianopoulos, E.; Liesenborghs, L.; Koch, M.; De Mol, M.; Autiero, M.; Wyns, S.; Plaisance, S.; Moons, L.; van Rooijen, N.; Giacca, M.; Stassen, J. -M.; Dewerchin, M.; Collen, D.; Carmeliet, P. |
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