PITZALIS, COSTANTINO
PITZALIS, COSTANTINO
Dipartimento Scienze Biomediche
A BAFF/APRIL-dependent TLR3-stimulated pathway enhances the capacity of rheumatoid synovial fibroblasts to induce AID expression and Ig class-switching in B cells
2011-01-01 Bombardieri, Michele; Kam, Ngar-Woon; Brentano, Fabia; Choi, Ken; Filer, Andrew; Kyburz, Diego; Mcinnes, Iain B; Gay, Steffen; Buckley, Christopher; Pitzalis, Costantino
A biomarker-based mathematical model to predict bone-forming potency of human synovial and periosteal mesenchymal stem cells
2008-01-01 De Bari, Cosimo; Dell'Accio, Francesco; Karystinou, Alexandra; Guillot, Pascale V.; Fisk, Nicholas M.; Jones, Elena A.; Mcgonagle, Dennis; Khan, Ilyas M.; Archer, Charles W.; Mitsiadis, Thimios A.; Nora Donaldson, Ana; Luyten, Frank P.; Pitzalis, Costantino
A homeostatic function of CXCR2 signalling in articular cartilage
2015-01-01 Sherwood, Joanna; Bertrand, Jessica; Nalesso, Giovanna; Poulet, Blandine; Pitsillides, Andrew; Brandolini, Laura; Karystinou, Alexandra; De Bari, Cosimo; Luyten, Frank P; Pitzalis, Costantino; Pap, Thomas; Dell'Accio, Francesco
A Multicenter Retrospective Analysis Evaluating Performance of Synovial Biopsy Techniques in Patients With Inflammatory Arthritis: Arthroscopic Versus Ultrasound-Guided Versus Blind Needle Biopsy
2018-01-01 Humby, Frances; Romão, Vasco C; Manzo, Antonio; Filer, Andrew; Bugatti, Serena; Vieira-Sousa, Elsa; Kelly, Stephen; Wechalekar, Mihir; Ahmed, Manzoor; Rocher, Vidalba; Hands, Rebecca; Montecucco, Carlomaurizio; Fonseca, Joao; Pitzalis, Costantino
A novel in vivo murine model of cartilage regeneration. Age and strain-dependent outcome after joint surface injury
2009-01-01 Eltawil, N. M.; De Bari, C.; Achan, P.; Pitzalis, C.; Dell'Accio, F.
A novel model for the pre-clinical imaging of inflamed human synovial vasculature
2009-01-01 Garrood, T.; Blades, M.; Haskard, D. O.; Mather, S.; Pitzalis, C.
A Pauci-Immune Synovial Pathotype Predicts Inadequate Response to TNFα-Blockade in Rheumatoid Arthritis Patients
2020-01-01 Nerviani, Alessandra; Di Cicco, Maria; Mahto, Arti; Lliso-Ribera, Gloria; Rivellese, Felice; Thorborn, Georgina; Hands, Rebecca; Bellan, Mattia; Mauro, Daniele; Boutet, Marie-Astrid; Giorli, Giovanni; Lewis, Myles; Kelly, Stephen; Bombardieri, Michele; Humby, Frances; Pitzalis, Costantino
Activation of naïve CD4+ T cells re-tunes STAT1 signaling to deliver unique cytokine responses in memory CD4+ T cells
2019-01-01 Twohig, Jason P; Cardus Figueras, Ana; Andrews, Robert; Wiede, Florian; Cossins, Benjamin C; Derrac Soria, Alicia; Lewis, Myles J; Townsend, Michael J; Millrine, David; Li, Jasmine; Hill, David G; Uceda Fernandez, Javier; Liu, Xiao; Szomolay, Barbara; Pepper, Christopher J; Taylor, Philip R; Pitzalis, Costantino; Tiganis, Tony; Williams, Nigel M; Jones, Gareth W; Jones, Simon A
Activation of WNT and BMP signaling in adult human articular cartilage following mechanical injury
2006-01-01 Dell'Accio, Francesco; De Bari, Cosimo; El Tawil, Noha M F; Barone, Francesca; Mitsiadis, Thimios A; O'Dowd, John; Pitzalis, Costantino
Acute serum amyloid A induces migration, angiogenesis, and inflammation in synovial cells in vitro and in a human rheumatoid arthritis/SCID mouse chimera model
2010-01-01 Connolly, Mary; Marrelli, Alessandra; Blades, Mark; Mccormick, Jennifer; Maderna, Paola; Godson, Catherine; Mullan, Ronan; Fitzgerald, Oliver; Bresnihan, Barry; Pitzalis, Costantino; Veale, Douglas J; Fearon, Ursula
ADAM10-Mediated ICOS Ligand Shedding on B Cells Is Necessary for Proper T Cell ICOS Regulation and T Follicular Helper Responses
2017-01-01 Lownik, Joseph C; Luker, Andrea J; Damle, Sheela R; Cooley, Lauren Folgosa; El Sayed, Riham; Hutloff, Andreas; Pitzalis, Costantino; Martin, Rebecca K; El Shikh, Mohey Eldin M; Conrad, Daniel H
Agrin induces long-term osteochondral regeneration by supporting repair morphogenesis
2020-01-01 Eldridge, Suzanne E; Barawi, Aida; Wang, Hui; Roelofs, Anke J; Kaneva, Magdalena; Guan, Zeyu; Lydon, Helen; Thomas, Bethan L; Thorup, Anne-Sophie; Fernandez, Beatriz F; Caxaria, Sara; Strachan, Danielle; Ali, Ahmed; Shanmuganathan, Kanatheepan; Pitzalis, Costantino; Whiteford, James R; Henson, Frances; Mccaskie, Andrew W; De Bari, Cosimo; Dell'Accio, Francesco
Analysis of Complement Gene Expression, Clinical Associations, and Biodistribution of Complement Proteins in the Synovium of Early Rheumatoid Arthritis Patients Reveals Unique Pathophysiologic Features
2022-01-01 Banda, Nirmal K; Deane, Kevin D; Bemis, Elizabeth A; Strickland, Colin; Seifert, Jennifer; Jordan, Kimberly; Goldman, Katriona; Morgan, B Paul; Moreland, Larry W; Lewis, Myles J; Pitzalis, Costantino; Holers, V Michael
Angiogenic gene expression and vascular density are reflected in ultrasonographic features of synovitis in early Rheumatoid Arthritis: an observational study
2015-01-01 Kelly, Stephen; Bombardieri, Michele; Humby, Frances; Ng, Nora; Marrelli, Alessandra; Riahi, Sudeh; Dicicco, Maria; Mahto, Arti; Zou, Lu; Pyne, Debasish; Hands, Rebecca E; Pitzalis, Costantino
Annexin 1 Modulates Monocyte-Endothelial Cell Interaction In Vitro and Cell Migration In Vivo in the Human SCID Mouse Transplantation Model
2002-01-01 Perretti, Mauro; Ingegnoli, Francesca; Wheller, Samantha K.; Blades, Mark C.; Solito, Egle; Pitzalis, Costantino
Anti-inflammatory and antiosteoclastogenesis properties of endogenous melanocortin receptor type 3 in experimental arthritis
2010-01-01 Patel, Hetal B.; Bombardieri, Michele; Sampaio, André L. F.; D'Acquisto, Fulvio; Gray, Mohini; Grieco, Paolo; Getting, Stephen J.; Pitzalis, Costantino; Perretti, Mauro
Anti-TNF-alpha agents and endothelial function in rheumatoid arthritis: a systematic review and meta-analysis
2017-01-01 Ursini, Francesco; Leporini, Christian; Bene, Fabiola; D'Angelo, Salvatore; Mauro, Daniele; Russo, Emilio; De Sarro, Giovambattista; Olivieri, Ignazio; Pitzalis, Costantino; Lewis, Myles; Grembiale, Rosa Daniela
Are differences in interleukin 10 production associated with joint damage?
2000-01-01 Huizinga, T. W. J.; Keijsers, V.; Yanni, G.; Hall, M.; Ramage, W.; Lanchbury, J.; Pitzalis, C.; Drossaers???bakker, W. K.; Westendorp, R. G. J.; Breedveld, F. C.; Panayi, G.; Verweij, C. L.
Association of response to TNF inhibitors in rheumatoid arthritis with quantitative trait loci for CD40 and CD39
2019-01-01 Spiliopoulou, Athina; Colombo, Marco; Plant, Darren; Nair, Nisha; Cui, Jing; Coenen, Marieke Jh; Ikari, Katsunori; Yamanaka, Hisashi; Saevarsdottir, Saedis; Padyukov, Leonid; Bridges, S Louis; Kimberly, Robert P; Okada, Yukinori; van Riel, Piet L Cm; Wolbink, Gertjan; van der Horst-Bruinsma, Irene E; de Vries, Niek; Tak, Paul P; Ohmura, Koichiro; Canhão, Helena; Guchelaar, Henk-Jan; Huizinga, Tom Wj; Criswell, Lindsey A; Raychaudhuri, Soumya; Weinblatt, Michael E; Wilson, Anthony G; Mariette, Xavier; Isaacs, John D; Morgan, Ann W; Pitzalis, Costantino; Barton, Anne; Mckeigue, Paul
Axl and MerTK regulate synovial inflammation and are modulated by IL-6 inhibition in rheumatoid arthritis
2024-01-01 Nerviani, Alessandra; Boutet, Marie-Astrid; Ghirardi, Giulia Maria; Goldmann, Katriona; Sciacca, Elisabetta; Rivellese, Felice; Pontarini, Elena; Prediletto, Edoardo; Abatecola, Federico; Caliste, Mattia; Pagani, Sara; Mauro, Daniele; Bellan, Mattia; Cubuk, Cankut; Lau, Rachel; Church, Sarah E.; Hudson, Briana M.; Humby, Frances; Bombardieri, Michele; Lewis, Myles J.; Pitzalis, Costantino
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| A BAFF/APRIL-dependent TLR3-stimulated pathway enhances the capacity of rheumatoid synovial fibroblasts to induce AID expression and Ig class-switching in B cells | 1-gen-2011 | Bombardieri, Michele; Kam, Ngar-Woon; Brentano, Fabia; Choi, Ken; Filer, Andrew; Kyburz, Diego; Mcinnes, Iain B; Gay, Steffen; Buckley, Christopher; Pitzalis, Costantino | |
| A biomarker-based mathematical model to predict bone-forming potency of human synovial and periosteal mesenchymal stem cells | 1-gen-2008 | De Bari, Cosimo; Dell'Accio, Francesco; Karystinou, Alexandra; Guillot, Pascale V.; Fisk, Nicholas M.; Jones, Elena A.; Mcgonagle, Dennis; Khan, Ilyas M.; Archer, Charles W.; Mitsiadis, Thimios A.; Nora Donaldson, Ana; Luyten, Frank P.; Pitzalis, Costantino | |
| A homeostatic function of CXCR2 signalling in articular cartilage | 1-gen-2015 | Sherwood, Joanna; Bertrand, Jessica; Nalesso, Giovanna; Poulet, Blandine; Pitsillides, Andrew; Brandolini, Laura; Karystinou, Alexandra; De Bari, Cosimo; Luyten, Frank P; Pitzalis, Costantino; Pap, Thomas; Dell'Accio, Francesco | |
| A Multicenter Retrospective Analysis Evaluating Performance of Synovial Biopsy Techniques in Patients With Inflammatory Arthritis: Arthroscopic Versus Ultrasound-Guided Versus Blind Needle Biopsy | 1-gen-2018 | Humby, Frances; Romão, Vasco C; Manzo, Antonio; Filer, Andrew; Bugatti, Serena; Vieira-Sousa, Elsa; Kelly, Stephen; Wechalekar, Mihir; Ahmed, Manzoor; Rocher, Vidalba; Hands, Rebecca; Montecucco, Carlomaurizio; Fonseca, Joao; Pitzalis, Costantino | |
| A novel in vivo murine model of cartilage regeneration. Age and strain-dependent outcome after joint surface injury | 1-gen-2009 | Eltawil, N. M.; De Bari, C.; Achan, P.; Pitzalis, C.; Dell'Accio, F. | |
| A novel model for the pre-clinical imaging of inflamed human synovial vasculature | 1-gen-2009 | Garrood, T.; Blades, M.; Haskard, D. O.; Mather, S.; Pitzalis, C. | |
| A Pauci-Immune Synovial Pathotype Predicts Inadequate Response to TNFα-Blockade in Rheumatoid Arthritis Patients | 1-gen-2020 | Nerviani, Alessandra; Di Cicco, Maria; Mahto, Arti; Lliso-Ribera, Gloria; Rivellese, Felice; Thorborn, Georgina; Hands, Rebecca; Bellan, Mattia; Mauro, Daniele; Boutet, Marie-Astrid; Giorli, Giovanni; Lewis, Myles; Kelly, Stephen; Bombardieri, Michele; Humby, Frances; Pitzalis, Costantino | |
| Activation of naïve CD4+ T cells re-tunes STAT1 signaling to deliver unique cytokine responses in memory CD4+ T cells | 1-gen-2019 | Twohig, Jason P; Cardus Figueras, Ana; Andrews, Robert; Wiede, Florian; Cossins, Benjamin C; Derrac Soria, Alicia; Lewis, Myles J; Townsend, Michael J; Millrine, David; Li, Jasmine; Hill, David G; Uceda Fernandez, Javier; Liu, Xiao; Szomolay, Barbara; Pepper, Christopher J; Taylor, Philip R; Pitzalis, Costantino; Tiganis, Tony; Williams, Nigel M; Jones, Gareth W; Jones, Simon A | |
| Activation of WNT and BMP signaling in adult human articular cartilage following mechanical injury | 1-gen-2006 | Dell'Accio, Francesco; De Bari, Cosimo; El Tawil, Noha M F; Barone, Francesca; Mitsiadis, Thimios A; O'Dowd, John; Pitzalis, Costantino | |
| Acute serum amyloid A induces migration, angiogenesis, and inflammation in synovial cells in vitro and in a human rheumatoid arthritis/SCID mouse chimera model | 1-gen-2010 | Connolly, Mary; Marrelli, Alessandra; Blades, Mark; Mccormick, Jennifer; Maderna, Paola; Godson, Catherine; Mullan, Ronan; Fitzgerald, Oliver; Bresnihan, Barry; Pitzalis, Costantino; Veale, Douglas J; Fearon, Ursula | |
| ADAM10-Mediated ICOS Ligand Shedding on B Cells Is Necessary for Proper T Cell ICOS Regulation and T Follicular Helper Responses | 1-gen-2017 | Lownik, Joseph C; Luker, Andrea J; Damle, Sheela R; Cooley, Lauren Folgosa; El Sayed, Riham; Hutloff, Andreas; Pitzalis, Costantino; Martin, Rebecca K; El Shikh, Mohey Eldin M; Conrad, Daniel H | |
| Agrin induces long-term osteochondral regeneration by supporting repair morphogenesis | 1-gen-2020 | Eldridge, Suzanne E; Barawi, Aida; Wang, Hui; Roelofs, Anke J; Kaneva, Magdalena; Guan, Zeyu; Lydon, Helen; Thomas, Bethan L; Thorup, Anne-Sophie; Fernandez, Beatriz F; Caxaria, Sara; Strachan, Danielle; Ali, Ahmed; Shanmuganathan, Kanatheepan; Pitzalis, Costantino; Whiteford, James R; Henson, Frances; Mccaskie, Andrew W; De Bari, Cosimo; Dell'Accio, Francesco | |
| Analysis of Complement Gene Expression, Clinical Associations, and Biodistribution of Complement Proteins in the Synovium of Early Rheumatoid Arthritis Patients Reveals Unique Pathophysiologic Features | 1-gen-2022 | Banda, Nirmal K; Deane, Kevin D; Bemis, Elizabeth A; Strickland, Colin; Seifert, Jennifer; Jordan, Kimberly; Goldman, Katriona; Morgan, B Paul; Moreland, Larry W; Lewis, Myles J; Pitzalis, Costantino; Holers, V Michael | |
| Angiogenic gene expression and vascular density are reflected in ultrasonographic features of synovitis in early Rheumatoid Arthritis: an observational study | 1-gen-2015 | Kelly, Stephen; Bombardieri, Michele; Humby, Frances; Ng, Nora; Marrelli, Alessandra; Riahi, Sudeh; Dicicco, Maria; Mahto, Arti; Zou, Lu; Pyne, Debasish; Hands, Rebecca E; Pitzalis, Costantino | |
| Annexin 1 Modulates Monocyte-Endothelial Cell Interaction In Vitro and Cell Migration In Vivo in the Human SCID Mouse Transplantation Model | 1-gen-2002 | Perretti, Mauro; Ingegnoli, Francesca; Wheller, Samantha K.; Blades, Mark C.; Solito, Egle; Pitzalis, Costantino | |
| Anti-inflammatory and antiosteoclastogenesis properties of endogenous melanocortin receptor type 3 in experimental arthritis | 1-gen-2010 | Patel, Hetal B.; Bombardieri, Michele; Sampaio, André L. F.; D'Acquisto, Fulvio; Gray, Mohini; Grieco, Paolo; Getting, Stephen J.; Pitzalis, Costantino; Perretti, Mauro | |
| Anti-TNF-alpha agents and endothelial function in rheumatoid arthritis: a systematic review and meta-analysis | 1-gen-2017 | Ursini, Francesco; Leporini, Christian; Bene, Fabiola; D'Angelo, Salvatore; Mauro, Daniele; Russo, Emilio; De Sarro, Giovambattista; Olivieri, Ignazio; Pitzalis, Costantino; Lewis, Myles; Grembiale, Rosa Daniela | |
| Are differences in interleukin 10 production associated with joint damage? | 1-gen-2000 | Huizinga, T. W. J.; Keijsers, V.; Yanni, G.; Hall, M.; Ramage, W.; Lanchbury, J.; Pitzalis, C.; Drossaers???bakker, W. K.; Westendorp, R. G. J.; Breedveld, F. C.; Panayi, G.; Verweij, C. L. | |
| Association of response to TNF inhibitors in rheumatoid arthritis with quantitative trait loci for CD40 and CD39 | 1-gen-2019 | Spiliopoulou, Athina; Colombo, Marco; Plant, Darren; Nair, Nisha; Cui, Jing; Coenen, Marieke Jh; Ikari, Katsunori; Yamanaka, Hisashi; Saevarsdottir, Saedis; Padyukov, Leonid; Bridges, S Louis; Kimberly, Robert P; Okada, Yukinori; van Riel, Piet L Cm; Wolbink, Gertjan; van der Horst-Bruinsma, Irene E; de Vries, Niek; Tak, Paul P; Ohmura, Koichiro; Canhão, Helena; Guchelaar, Henk-Jan; Huizinga, Tom Wj; Criswell, Lindsey A; Raychaudhuri, Soumya; Weinblatt, Michael E; Wilson, Anthony G; Mariette, Xavier; Isaacs, John D; Morgan, Ann W; Pitzalis, Costantino; Barton, Anne; Mckeigue, Paul | |
| Axl and MerTK regulate synovial inflammation and are modulated by IL-6 inhibition in rheumatoid arthritis | 1-gen-2024 | Nerviani, Alessandra; Boutet, Marie-Astrid; Ghirardi, Giulia Maria; Goldmann, Katriona; Sciacca, Elisabetta; Rivellese, Felice; Pontarini, Elena; Prediletto, Edoardo; Abatecola, Federico; Caliste, Mattia; Pagani, Sara; Mauro, Daniele; Bellan, Mattia; Cubuk, Cankut; Lau, Rachel; Church, Sarah E.; Hudson, Briana M.; Humby, Frances; Bombardieri, Michele; Lewis, Myles J.; Pitzalis, Costantino |